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Prevalence and Risk Factors of Childhood Hypertension in Urban-Rural Areas of China: A Cross-Sectional Study

Overview
Journal Int J Hypertens
Publisher Wiley
Date 2020 May 27
PMID 32454994
Citations 15
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Abstract

Objective: The increased blood pressure level in children and adolescents is recognized as an essential predictor of adulthood cardiovascular disease. This study aimed to ascertain the prevalence and the urban-rural disparity of childhood hypertension in the southwest of China.

Methods: Using stratified cluster sampling in urban and rural areas, a total of 13597 primary school children aged 6∼12 years living in the Southwest of China were included. The prevalence of hypertension was analyzed. The risk factors were collected by questionnaires, and the risk factors of childhood hypertension were analyzed by the logistic regression model.

Results: The prevalence of hypertension was 13.75%, 9.02%, and 17.47% in total, urban, and rural children, respectively, and the urban-rural difference was 8.44% (95%CI: 7.32%, 9.56%). Children with obesity, maternal gestational hypertension, >10 months of breastfeeding, or low family income had a significantly increased prevalence of hypertension (29.4%, 20.00%, 16.31%, and 16.25%, respectively). Rural residence, intake of more pickle (in rural), maternal gestational hypertension (in urban), low birth weight (in rural), obesity, increased heart rate, and red blood cell counts were the risk factors of childhood hypertension. The adjusted values were 13.61%, 23.25%, 10.88%, 11.12%, 12.23%, and 25.04% in the full models excluding and including serum indexes for total, urban, and rural children, respectively.

Conclusions: The prevalence of childhood hypertension is significant in the Southwest of China and alarming in rural areas, which requires community intervention. Children living in rural areas combined with obesity, low social economic status, dietary imbalance, and abnormal lipid metabolism were associated with an increased risk of hypertension, and routine care programs should be conducted to prevent childhood hypertension.

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References
1.
Onsuz F, Demir F . Prevalence of hypertension and its association with obesity among school children aged 6-15 living in Sakarya Province in Turkey. Turk J Med Sci. 2015; 45(4):907-12. View

2.
Kuhle S, Maguire B, Ata N, MacInnis N, Dodds L . Birth Weight for Gestational Age, Anthropometric Measures, and Cardiovascular Disease Markers in Children. J Pediatr. 2016; 182:99-106. DOI: 10.1016/j.jpeds.2016.11.067. View

3.
Huxley R, Shiell A, Law C . The role of size at birth and postnatal catch-up growth in determining systolic blood pressure: a systematic review of the literature. J Hypertens. 2000; 18(7):815-31. DOI: 10.1097/00004872-200018070-00002. View

4.
Ikeda N, Fuse K, Nishi N . Changes in the effects of living with no siblings or living with grandparents on overweight and obesity in children: Results from a national cohort study in Japan. PLoS One. 2017; 12(4):e0175726. PMC: 5393582. DOI: 10.1371/journal.pone.0175726. View

5.
Karatzi K, Protogerou A, Moschonis G, Tsirimiagou C, Androutsos O, Chrousos G . Prevalence of hypertension and hypertension phenotypes by age and gender among schoolchildren in Greece: The Healthy Growth Study. Atherosclerosis. 2017; 259:128-133. DOI: 10.1016/j.atherosclerosis.2017.01.027. View