» Articles » PMID: 32445417

Expansion of Hospital-based Blood Collections in the Face of COVID-19 Associated National Blood Shortage

Overview
Journal Transfusion
Specialty Hematology
Date 2020 May 24
PMID 32445417
Citations 23
Authors
Affiliations
Soon will be listed here.
Abstract

Background: When the coronavirus pandemic caused widespread school and business closures in March 2020, blood drives were canceled and the supply of blood decreased suddenly in the United States (US). In response, hospital-based transfusion medicine physicians instituted policies to conserve blood and decrease blood product usage. These efforts were aided by the US Surgeon General recommendation to cancel all elective procedures. Nevertheless, the duration, severity, and impact of the pandemic on the national blood supply was uncertain. Hospitals with in-house donor programs had the opportunity not only to control demand, but also increase supply.

Study Design And Methods: A hospital-based blood donor center was rapidly mobilized to increase the supply of in-house collected blood, in order to counteract a sudden but potentially long-term depletion of the national blood supply during a pandemic.

Results: Collections increased approximately five-fold above baseline for whole blood units, while apheresis platelet units were maintained at the historical average for the blood donor center. Cancellation of elective procedures showed a modest, but not yet statistically significant decrease in average blood product usage per day, nevertheless the in-house collection rate was sufficient to meet demand.

Conclusion: A hospital-based blood donor center can quickly increase collection volumes and capacity in the face of a national emergency or pandemic. The desire to collect units should be balanced with safety concerns, need for sustainability, and blood product demand.

Citing Articles

Impact of the COVID-19 Pandemic on Blood Transfusion among Hospitalized Patients with Chronic Kidney Disease.

Ali S, Botnarciuc M, Badea I, Alexandru A, Tuta L, Daba L Medicina (Kaunas). 2024; 60(9).

PMID: 39336553 PMC: 11434223. DOI: 10.3390/medicina60091512.


Red Blood Cell Membrane-Coated Nanoparticles Enable Incompatible Blood Transfusions.

Yang X, Chen M, Weng C, Zhuge D, Jin F, Xiao Y Adv Sci (Weinh). 2024; 11(29):e2310230.

PMID: 38837643 PMC: 11304279. DOI: 10.1002/advs.202310230.


COVID-19 impact on blood donor characteristics and seroprevalence of transfusion-transmitted infections in southern Thailand between 2018 and 2022.

Burananayok S, Nachatri W, Choothanorm P, Kusolthammarat K, Jaruthamsophon K, Yodsawad C Sci Rep. 2024; 14(1):7920.

PMID: 38575642 PMC: 10995202. DOI: 10.1038/s41598-024-57584-z.


Supplemental findings of the 2021 National Blood Collection and Utilization Survey.

Kracalik I, Sapiano M, Wild R, Chavez Ortiz J, Stewart P, Berger J Transfusion. 2023; 63 Suppl 4:S19-S42.

PMID: 37702255 PMC: 10783319. DOI: 10.1111/trf.17509.


Design of the Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery.

Whitman G, Kramer R, Tanaka K, Holcomb J, Fitzpatrick G, Raphael J JTCVS Open. 2023; 13:232-241.

PMID: 37063119 PMC: 10091215. DOI: 10.1016/j.xjon.2022.11.003.


References
1.
Popovsky M . Should hospitals collect blood components?: no. Transfus Sci. 1997; 18(4):545-51. DOI: 10.1016/s0955-3886(97)00052-0. View

2.
Pagano M, Hess J, Tsang H, Staley E, Gernsheimer T, Sen N . Prepare to adapt: blood supply and transfusion support during the first 2 weeks of the 2019 novel coronavirus (COVID-19) pandemic affecting Washington State. Transfusion. 2020; 60(5):908-911. DOI: 10.1111/trf.15789. View

3.
Chen L, Xiong J, Bao L, Shi Y . Convalescent plasma as a potential therapy for COVID-19. Lancet Infect Dis. 2020; 20(4):398-400. PMC: 7128218. DOI: 10.1016/S1473-3099(20)30141-9. View

4.
Ellingson K, Sapiano M, Haass K, Savinkina A, Baker M, Chung K . Continued decline in blood collection and transfusion in the United States-2015. Transfusion. 2017; 57 Suppl 2:1588-1598. PMC: 5556921. DOI: 10.1111/trf.14165. View

5.
Lai C, Liu Y, Wang C, Wang Y, Hsueh S, Yen M . Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths. J Microbiol Immunol Infect. 2020; 53(3):404-412. PMC: 7128959. DOI: 10.1016/j.jmii.2020.02.012. View