Comparative Study of the Composition of Sweat from Eccrine and Apocrine Sweat Glands During Exercise and in Heat

Overview

Journal Int J Environ Res Public Health

Publisher MDPI

Specialties Environmental Health
Public Health

Date 2020 May 16

PMID 32408694

Citations 11

Authors

Yi-Lang Chen

Wen-Hui Kuan

Chao-Lin Liu

Affiliations

Soon will be listed here.

Abstract

This preliminarily study was made to examine the differences in sweat excretions from human eccrine and apocrine sweat glands in dynamic exercise and heat conditions. Sweat samples were collected from six young males while they were either running on a treadmill or sitting in a sauna cabinet. Sweat samples of at least 5 mL from the eccrine (upperback) and apocrine (armpit) sweat glands were collected during a 20min running (or inactive overheating) period. The samples were then analyzed for urea, uric acid, and electrolyte (Na, Cl, and K) excretions. The results from a twoway repeatedmeasures analysis of variance (ANOVA) revealed that the secretions of urea and K were significantly higher during running than during inactive overheating for both glands, as were Na secretions for the apocrine glands (all P < 0.05). Under the same sweating conditions, urea and K excretions from the apocrine glands were also higher than those from the eccrine glands (all P < 0.05). Significant differences were observed between the Na secretions of the apocrine and eccrine glands under the running condition. The effects of various sweating methods and sweat glands on Cl secretions were nonsignificant, and little uric acid was excreted. A higher urea excretion level during running rather than in hot conditions could be attributed to an elevated metabolic rate.

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References

Dill D, Hall F, VAN BEAUMONT W . Sweat chloride concentration: sweat rate, metabolic rate, skin temperature, and age. J Appl Physiol. 1966; 21(1):99-106. DOI: 10.1152/jappl.1966.21.1.99. View

Sato K, Sato F . Sweat secretion by human axillary apoeccrine sweat gland in vitro. Am J Physiol. 1987; 252(1 Pt 2):R181-7. DOI: 10.1152/ajpregu.1987.252.1.R181. View

Wilke K, Martin A, Terstegen L, Biel S . A short history of sweat gland biology. Int J Cosmet Sci. 2008; 29(3):169-79. DOI: 10.1111/j.1467-2494.2007.00387.x. View

Baker L . Sweating Rate and Sweat Sodium Concentration in Athletes: A Review of Methodology and Intra/Interindividual Variability. Sports Med. 2017; 47(Suppl 1):111-128. PMC: 5371639. DOI: 10.1007/s40279-017-0691-5. View

Berenson G, BURCH G . The response of patients with congestive heart failure to a rapid elevation in atmospheric temperature and humidity. Am J Med Sci. 1952; 223(1):45-53. DOI: 10.1097/00000441-195201000-00008. View

Huxley H . The mechanism of muscular contraction. Science 164:1356-1366, 1969. Clin Orthop Relat Res. 2002; (403 Suppl):S6-17. View

Taylor R, Polliack A, Bader D . The analysis of metabolites in human sweat: analytical methods and potential application to investigation of pressure ischaemia of soft tissues. Ann Clin Biochem. 1994; 31 ( Pt 1):18-24. DOI: 10.1177/000456329403100103. View

Dutkiewicz E, Lin J, Tseng T, Wang Y, Urban P . Hydrogel micropatches for sampling and profiling skin metabolites. Anal Chem. 2014; 86(5):2337-44. DOI: 10.1021/ac4039338. View

Taylor N, Machado-Moreira C . Regional variations in transepidermal water loss, eccrine sweat gland density, sweat secretion rates and electrolyte composition in resting and exercising humans. Extrem Physiol Med. 2013; 2(1):4. PMC: 3710196. DOI: 10.1186/2046-7648-2-4. View

10.

Groscurth P . Anatomy of sweat glands. Curr Probl Dermatol. 2002; 30:1-9. DOI: 10.1159/000060678. View

11.

Al-Tamer Y, Hadi E . Sweat urea, uric acid and creatinine concentrations in uraemic patients. Urol Res. 1997; 25(5):337-40. DOI: 10.1007/BF01294662. View

12.

Jadoon S, Karim S, Akram M, Khan A, Zia M, Siddiqi A . Recent developments in sweat analysis and its applications. Int J Anal Chem. 2015; 2015:164974. PMC: 4369929. DOI: 10.1155/2015/164974. View

13.

Ely M, Kenefick R, Cheuvront S, Chinevere T, Lacher C, Lukaski H . Surface contamination artificially elevates initial sweat mineral concentrations. J Appl Physiol (1985). 2011; 110(6):1534-40. DOI: 10.1152/japplphysiol.01437.2010. View

14.

Verde T, Shephard R, Corey P, MOORE R . Sweat composition in exercise and in heat. J Appl Physiol Respir Environ Exerc Physiol. 1982; 53(6):1540-5. DOI: 10.1152/jappl.1982.53.6.1540. View

15.

Fellmann N, Labbe A, Gachon A, Coudert J . Thermal sweat lactate in cystic fibrosis and in normal children. Eur J Appl Physiol Occup Physiol. 1985; 54(5):511-6. DOI: 10.1007/BF00422962. View

16.

Fyhrquist N, Salava A, Auvinen P, Lauerma A . Skin Biomes. Curr Allergy Asthma Rep. 2016; 16(5):40. DOI: 10.1007/s11882-016-0618-5. View

17.

CONSOLAZIO C, MATOUSH L, Nelson R, Hackler L, Preston E . Relationship between calcium in sweat, calcium balance, and calcium requirements. J Nutr. 1962; 78:78-88. DOI: 10.1093/jn/78.1.78. View

18.

Fukumoto T, Tanaka T, Fujioka H, Yoshihara S, Ochi T, Kuroiwa A . Differences in composition of sweat induced by thermal exposure and by running exercise. Clin Cardiol. 1988; 11(10):707-9. DOI: 10.1002/clc.4960111010. View

19.

Vairo D, Bruzzese L, Marlinge M, Fuster L, Adjriou N, Kipson N . Towards Addressing the Body Electrolyte Environment via Sweat Analysis:Pilocarpine Iontophoresis Supports Assessment of Plasma Potassium Concentration. Sci Rep. 2017; 7(1):11801. PMC: 5603548. DOI: 10.1038/s41598-017-12211-y. View

20.

GARDEN J . Plasma and sweat histamine concentrations after heat exposure and physical exercise. J Appl Physiol. 1966; 21(2):631-5. DOI: 10.1152/jappl.1966.21.2.631. View