Special Issue About Head and Neck Cancers: HPV Positive Cancers

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2020 May 15

PMID 32403287

Citations 33

Authors

Panagiota Economopoulou

Ioannis Kotsantis

Amanda Psyrri

Affiliations

Soon will be listed here.

Abstract

The oropharynx has become the leading primary site for Human Papilloma Virus (HPV)-associated head and neck cancer. HPV positive oropharyngeal squamous cell carcinoma (HPV+ OSCC) has emerged as an epidemic not easily recognized by many physicians, resulting in delays in diagnosis and management. HPV+ OSCC traditionally refers to younger, healthier patients with high economic status and high-risk sexual behavior and is related to improved prognosis. De-intensification strategies are being evaluated in ongoing clinical trials and if validated, might help spare severe morbidity associated with current cisplatin-based chemoradiotherapy, which is the standard of care for all patients with locally advanced head and neck cancer. On the other hand, whether HPV status represents an important prognostic factor for non-oropharyngeal sites remains to be elucidated.

Citing Articles

Circulating HPV Tumor DNA and Molecular Residual Disease in HPV-Positive Oropharyngeal Cancers: A Scoping Review.

Migliorelli A, Ciorba A, Manuelli M, Stomeo F, Pelucchi S, Bianchini C Diagnostics (Basel). 2024; 14(23).

PMID: 39682570 PMC: 11640492. DOI: 10.3390/diagnostics14232662.

Role of Artificial Intelligence in Human Papillomavirus Status Prediction for Oropharyngeal Cancer: A Scoping Review.

Migliorelli A, Manuelli M, Ciorba A, Stomeo F, Pelucchi S, Bianchini C Cancers (Basel). 2024; 16(23).

PMID: 39682226 PMC: 11640028. DOI: 10.3390/cancers16234040.

Understanding the HPV associated cancers: A comprehensive review.

Balhara N, Yadav R, Ranga S, Ahuja P, Tanwar M Mol Biol Rep. 2024; 51(1):743.

PMID: 38874682 DOI: 10.1007/s11033-024-09680-6.

Relationship between vaginal and oral microbiome in patients of human papillomavirus (HPV) infection and cervical cancer.

Zhang W, Yin Y, Jiang Y, Yang Y, Wang W, Wang X J Transl Med. 2024; 22(1):396.

PMID: 38685022 PMC: 11059664. DOI: 10.1186/s12967-024-05124-8.

A systematic literature review of the human papillomavirus prevalence in locally and regionally advanced and recurrent/metastatic head and neck cancers through the last decade: The "ALARM" study.

Agelaki S, Boukovinas I, Athanasiadis I, Trimis G, Dimitriadis I, Poughias L Cancer Med. 2024; 13(3):e6916.

PMID: 38247106 PMC: 10905345. DOI: 10.1002/cam4.6916.

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