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Thalamic, Cortical, and Amygdala Involvement in the Processing of a Natural Sound Cue of Danger

Overview
Journal PLoS Biol
Specialty Biology
Date 2020 May 13
PMID 32396574
Citations 3
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Abstract

Animals use auditory cues generated by defensive responses of others to detect impending danger. Here we identify a neural circuit in rats involved in the detection of one such auditory cue, the cessation of movement-evoked sound resulting from freezing. This circuit comprises the dorsal subnucleus of the medial geniculate body (MGD) and downstream areas, the ventral area of the auditory cortex (VA), and the lateral amygdala (LA). This study suggests a role for the auditory offset pathway in processing a natural sound cue of threat.

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References
1.
Yang Y, Liu D, Huang W, Deng J, Sun Y, Zuo Y . Selective synaptic remodeling of amygdalocortical connections associated with fear memory. Nat Neurosci. 2016; 19(10):1348-55. DOI: 10.1038/nn.4370. View

2.
Romanski L, LeDoux J . Information cascade from primary auditory cortex to the amygdala: corticocortical and corticoamygdaloid projections of temporal cortex in the rat. Cereb Cortex. 1993; 3(6):515-32. DOI: 10.1093/cercor/3.6.515. View

3.
He J . OFF responses in the auditory thalamus of the guinea pig. J Neurophysiol. 2002; 88(5):2377-86. DOI: 10.1152/jn.00083.2002. View

4.
Smith P, Uhlrich D, Manning K, Banks M . Thalamocortical projections to rat auditory cortex from the ventral and dorsal divisions of the medial geniculate nucleus. J Comp Neurol. 2011; 520(1):34-51. PMC: 3320111. DOI: 10.1002/cne.22682. View

5.
Catania K, Hare J, Campbell K . Water shrews detect movement, shape, and smell to find prey underwater. Proc Natl Acad Sci U S A. 2008; 105(2):571-6. PMC: 2206577. DOI: 10.1073/pnas.0709534104. View