Life Expectancy and Survival Analysis of Patients with Diabetes Compared to the Non Diabetic Population in Bulgaria

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2020 May 12

PMID 32392235

Citations 13

Authors

Konstantin Tachkov

Konstantin Mitov

Yordanka Koleva

Zornitsa Mitkova

Maria Kamusheva

Maria Dimitrova

Valentina Petkova

Alexandra Savova

Miglena Doneva

Dimitar Tcarukciev

Vasil Valov

Galia Angelova

Manoela Manova

Guenka Petrova

Affiliations

Soon will be listed here.

Abstract

Aims: To evaluate the expected life expectancy in patients with diabetes in Bulgaria and to compare it to the expected life expectancy of the non-diabetic population in the country.

Methods: It is a retrospective observational population study on individuals diagnosed with diabetes, compared to the non-diabetic population in Bulgaria for the period 2012-2015. Data from the national diabetes register and national statistical institute were used to construct life-tables with probability of survival with t-test and Chi Square test. Confounder analysis was done by age, sex, and type of diabetes. All-cause mortality and deaths in diabetic patients were analyzed. Kaplan-Meier survival curves were constructed for each age group and a log-rank analysis was conducted.

Results: Average life expectancy in the non-diabetic population, patients with Type 1 DM and with Type 2 DM is 74.8; 70.96 and 75.19 years, respectively. For 2012-2015 the mortality in the non-diabetic population remained constant and lower (average-1.48%) compared to type-1 DM (5.25%) and Type-2 (4.27%). Relative risk of death in diabetics was higher overall (12%), after the age of 70 before which the relative risk was higher for the non-diabetic population. This was observed as a trend in all analyzed years.

Conclusion: Patients with type 2 DM have a longer life-expectancy than patients with type-1 DM and overall Diabetics life expectancy equals that of the non-diabetic population, which could suggest improved disease control and its associated complications in Bulgaria. Male diabetics show slightly longer life expectancy than their counterparts in the non-diabetic population, by a marginal gain of 0.6 years for the entire observed period. Life expectancy in diabetic women increased by 1.3 years, which was not observed in the non-diabetic population. Prevalence of diabetes was higher for women. Improved diabetes control may explain this gain in life; however other studies are needed to confirm this.

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