Connecting Pathological Cellular Mechanisms to Large-Scale Seizure Structures
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Abstract
Epilepsy is a neurological disorder characterized by recurrent seizures, where abnormal electrical activity begins in a local brain area and propagates before terminating. In a recent study, Liou and colleagues used multiscale computational modeling to gain mechanistic insights into clinical seizure dynamics based on cellular-level biophysical properties.
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Smith E, Liou J, Merricks E, Davis T, Thomson K, Greger B Elife. 2022; 11.
PMID: 35050851 PMC: 8813051. DOI: 10.7554/eLife.73541.
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