Endoscopic Closure of Refractory Esophageal Fistula After Esophagectomy Using Polyglycolic Acid Sheets: a Pilot Study

Overview

Journal Endosc Int Open

Specialty Gastroenterology

Date 2020 May 2

PMID 32355875

Citations 5

Authors

Yasuaki Nagami

Masaki Ominami

Taishi Sakai

Shusei Fukunaga

Fumio Tanaka

Koichi Taira

Tetsuya Tanigawa

Shigeru Lee

Toshio Watanabe

Yasuhiro Fujiwara

Affiliations

Soon will be listed here.

Abstract

Esophageal fistulas after esophagectomy are associated with high mortality and poor quality of life. They are sometimes intractable to conservative management and surgery that increases mortality. Few studies have assessed use of polyglycolic acid (PGA) sheets with fibrin glue for esophageal fistulas. We investigated the safety of using PGA sheets with fibrin glue for esophageal fistulas after esophagectomy. This was a single-center prospective pilot study. Patients who had refractory esophageal fistulas after esophagectomy were included. PGA sheets were filled in the fistula using biopsy forceps. Fibrin glue was applied to the PGA sheets. We repeated the procedure 1 week later. The outcome measures were the incidence of adverse events (AEs) and closure of the fistula. Five patients were assessed. No adverse events were observed. The esophageal fistula was closed with the application of PGA sheets four times in 40 % (2/5) of the cases. PGA sheets with fibrin glue were safe for esophageal fistula closure after esophagectomy and do not involve the risk of AEs.

Citing Articles

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A pediatric case of endoscopic fistula closure using a polyglycolic acid sheet.

Kono M, Nagami Y, Nakaoka T, Matsuki A, Ominami M, Fukunaga S Endoscopy. 2023; 55(S 01):E825-E826.

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Evaluation of the Effects of Covering With Polyglycolic Acid Sheet on Wound Healing: A Pilot Histopathological Study.

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Three-step operation for esophago-left bronchial fistula with respiratory failure after esophagectomy: a case report with literature review.

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