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Childhood Diarrhoeal Diseases in Developing Countries

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Journal Heliyon
Specialty Social Sciences
Date 2020 Apr 24
PMID 32322707
Citations 64
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Abstract

Diarrhoeal diseases collectively constitute a serious public health challenge globally, especially as the leading cause of death in children (after respiratory diseases). Childhood diarrhoea affecting children under the age of five accounts for approximately 63% of the global burden. Accurate and timely detection of the aetiology of these diseases is very crucial; but conventional methods, apart from being laborious and time-consuming, often fail to identify difficult-to-culture pathogens. The aetiological agent of an average of up to 40% of cases of diarrhoea cannot be identified. This review gives an overview of the recent trends in the epidemiology and treatment of diarrhoea and aims at highlighting the potentials of metagenomics technique as a diagnostic method for enteric infections.

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References
1.
Giannattasio A, Guarino A, Lo Vecchio A . Management of children with prolonged diarrhea. F1000Res. 2016; 5. PMC: 4765715. DOI: 10.12688/f1000research.7469.1. View

2.
Onanuga A, Igbeneghu O, Lamikanra A . A study of the prevalence of diarrhoeagenic Escherichia coli in children from Gwagwalada, Federal Capital Territory, Nigeria. Pan Afr Med J. 2014; 17:146. PMC: 4219803. DOI: 10.11604/pamj.2014.17.146.3369. View

3.
Liu L, Johnson H, Cousens S, Perin J, Scott S, Lawn J . Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012; 379(9832):2151-61. DOI: 10.1016/S0140-6736(12)60560-1. View

4.
Thakur N, Jain S, Changotra H, Shrivastava R, Kumar Y, Grover N . Molecular characterization of diarrheagenic Escherichia coli pathotypes: Association of virulent genes, serogroups, and antibiotic resistance among moderate-to-severe diarrhea patients. J Clin Lab Anal. 2018; 32(5):e22388. PMC: 6816858. DOI: 10.1002/jcla.22388. View

5.
Barnes D, Park K . Donor Considerations in Fecal Microbiota Transplantation. Curr Gastroenterol Rep. 2017; 19(3):10. DOI: 10.1007/s11894-017-0548-y. View