» Articles » PMID: 32321061

The Association Between Neurocognitive Functioning and Clinical Features of Borderline Personality Disorder

Overview
Specialty Psychiatry
Date 2020 Apr 23
PMID 32321061
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To investigate the relationship between neurocognitive profiles and clinical manifestations of borderline personality disorder (BPD).

Methods: Forty-five patients diagnosed with BPD and 35 healthy volunteers were included in the study. The BPD group was evaluated with the Borderline Personality Inventory for dissociative, impulsivity and suicidal dimensions. The Verbal Memory Processes Test and the Cambridge Neurophysiological Assessment Battery were administered to both the BPD and healthy control groups.

Results: BPD patients differed from controls in sustained attention, facial emotion recognition, and deteriorated verbal memory function. A model consisting of the Dissociative Experiences Scale - Taxon (DES-T), motor impulsivity and Scale for Suicidal Behavior scores explained 52% of the variance in Borderline Personality Inventory scores. It was detected that motor impulsivity, decision-making and recognizing sadness may significantly predict DES-T scores, and response inhibition and facial emotion recognition scores may significantly predict impulsivity.

Conclusion: Our findings demonstrate that the disassociation, impulsivity, and suicidality dimensions are sufficient to represent the clinical manifestations of BPD, that they are related to neurocognitive differences, and that they interact with clinical features.

Citing Articles

Borderline personality disorder and risk of atrial fibrillation: insights from a bidirectional Mendelian randomization study.

Zhou W, Wang Z, Hu H, Shi Y, Wang Q, Xue M Front Psychiatry. 2024; 15:1392605.

PMID: 39050916 PMC: 11266161. DOI: 10.3389/fpsyt.2024.1392605.


The Relationship of the Impulsivity and Decision-Making Behavior with Social Cognitive Skills in Borderline Personality Disorder.

Vatansever B, Buyukgok D, Aypak O, Ercis M, Sahin D Noro Psikiyatr Ars. 2024; 61(2):119-127.

PMID: 38868843 PMC: 11165603. DOI: 10.29399/npa.28439.


Association of Intronic C>T Single Nucleotide Polymorphism (rs782440) with Borderline Personality Disorder: A Case-Control Study.

Hatami Bavarsad N, Jahangard L, Saidijam M, Karimi S, Soltanian A, Shahriari E Cell J. 2023; 25(11):783-789.

PMID: 38071410 PMC: 10711293. DOI: 10.22074/cellj.2023.2004323.1321.


Impaired decision-making in borderline personality disorder.

Bajzat B, Soltesz P, Soltesz-Varhelyi K, Levay E, Unoka Z Front Psychol. 2023; 14:1109238.

PMID: 37599767 PMC: 10436614. DOI: 10.3389/fpsyg.2023.1109238.


The Role of Cognitive Deficits in Borderline Personality Disorder with Early Traumas: A Mediation Analysis.

Bozzatello P, Blua C, Brasso C, Rocca P, Bellino S J Clin Med. 2023; 12(3).

PMID: 36769436 PMC: 9917894. DOI: 10.3390/jcm12030787.


References
1.
Faul F, Erdfelder E, Buchner A, Lang A . Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods. 2009; 41(4):1149-60. DOI: 10.3758/BRM.41.4.1149. View

2.
Shearer S . Dissociative phenomena in women with borderline personality disorder. Am J Psychiatry. 1994; 151(9):1324-8. DOI: 10.1176/ajp.151.9.1324. View

3.
Adolphs R, Spezio M . Role of the amygdala in processing visual social stimuli. Prog Brain Res. 2006; 156:363-78. DOI: 10.1016/S0079-6123(06)56020-0. View

4.
Zlotnick C, Johnson D, Yen S, Battle C, Sanislow C, Skodol A . Clinical features and impairment in women with Borderline Personality Disorder (BPD) with Posttraumatic Stress Disorder (PTSD), BPD without PTSD, and other personality disorders with PTSD. J Nerv Ment Dis. 2003; 191(11):706-13. DOI: 10.1097/01.nmd.0000095122.29476.ff. View

5.
Skodol A, Siever L, Livesley W, Gunderson J, Pfohl B, Widiger T . The borderline diagnosis II: biology, genetics, and clinical course. Biol Psychiatry. 2002; 51(12):951-63. DOI: 10.1016/s0006-3223(02)01325-2. View