Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection

Overview

Journal Virus Res

Specialty Microbiology

Date 2020 Apr 21

PMID 32311386

Citations 57

Authors

Tong-Qing An

Jiang-Nan Li

Chia-Ming Su

Dongwan Yoo

Affiliations

Soon will be listed here.

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection, and it is evident that PRRSV has evolved to equip various strategies to disrupt the host antiviral system and provide favorable conditions for survival. The current study reviews viral strategies for modulations of cellular processes including innate immunity, apoptosis, microRNAs, inflammatory cytokines, and other cellular pathways.

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