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Features of Anosmia in COVID-19

Overview
Journal Med Mal Infect
Publisher Elsevier
Specialties General Medicine
Infectious Diseases
Date 2020 Apr 20
PMID 32305563
Citations 232
Authors
T Klopfenstein
N J Kadiane-Oussou
L Toko
P-Y Royer
Q Lepiller
V Gendrin
S Zayet
Affiliations
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Abstract

Background: Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients.

Methods: We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in respiratory samples to confirm the cases.

Results: Fifty-four of 114 patients (47%) with confirmed COVID-19 reported anosmia. Mean age of the 54 patients was 47 (±16) years; 67% were females and 37% were hospitalised. The median Charlson comorbidity index was 0.70 (±1.6 [0-7]). Forty-six patients (85%) had dysgeusia and 28% presented with pneumonia. Anosmia began 4.4 (±1.9 [1-8]) days after infection onset. The mean duration of anosmia was 8.9 (±6.3 [1-21]) days and 98% of patients recovered within 28 days.

Conclusions: Anosmia was present in half of our European COVID-19 patients and was often associated with dysgeusia.

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