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[A Case of Cholinergic Crisis with Persistent Watery Diarrhea]

Overview
Specialty Gastroenterology
Date 2020 Apr 14
PMID 32281572
Citations 1
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Abstract

The patient was a 79-year-old man who visited our hospital with the chief complaint of persistent watery diarrhea. This symptom and his general condition aggravated during the planning of colonoscopy, and he was admitted to the intensive care unit. Large-volume fluid replacement, vasopressor administration, and artificial respiration management were performed;however, circulatory dynamics did not improve. Based on his medication history, he was diagnosed with distigmine bromide-induced cholinergic crisis. Atropine sulfate was administered, and his symptoms reduced. On colonoscopy, there were no abnormal findings other than adenoma, and the patient was discharged while in remission.

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Cholinergic Crisis Owing to Distigmine Bromide Complicated by Hyperosmolar Hyperglycemic State.

Kotake K, Tone A, Watanabe S, Senoo M, Kaneto M, Imai Y Intern Med. 2021; 60(14):2251-2254.

PMID: 33583891 PMC: 8355397. DOI: 10.2169/internalmedicine.6261-20.