» Articles » PMID: 32277298

Fibrocalculous Pancreatic Diabetes

Overview
Journal Curr Diab Rep
Publisher Current Science
Specialty Endocrinology
Date 2020 Apr 12
PMID 32277298
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose Of Review: Fibrocalculous pancreatic diabetes (FCPD) is an uncommon form of diabetes occurring in underprivileged developing countries of the world. We attempt to review the latest evidence on epidemiology, secular trends, etiopathogenic mechanisms, and treatment modalities of FCPD with particular reference to studies from the past decade.

Recent Findings: There has been little new data on FCPD over the past decade even from countries where it was considered to be prevalent. There appears to be a decline in prevalence of the condition of late. There is also some evidence to show that the condition develops due to as yet unknown environmental influences acting on a background of genetic susceptibility. FCPD is a severe form of diabetes and may be a premalignant condition. FCPD deserves more attention than it currently receives, because of its unique clinical features and management strategies, and its propensity to develop pancreatic adenocarcinoma.

Citing Articles

Non-tropical fibrocalculous pancreatic diabetes: case reports and review of recent literature.

Xia F, Zhou W, Wang B, Hu Y J Int Med Res. 2020; 48(7):300060520938967.

PMID: 32691650 PMC: 7375728. DOI: 10.1177/0300060520938967.

References
1.
McMillan D, Geevarghese P . Dietary cyanide and tropical malnutrition diabetes. Diabetes Care. 1979; 2(2):202-8. DOI: 10.2337/diacare.2.2.202. View

2.
Balaji L, Tandon R, Tandon B, Banks P . Prevalence and clinical features of chronic pancreatitis in southern India. Int J Pancreatol. 1994; 15(1):29-34. DOI: 10.1007/BF02924385. View

3.
Mohan V, Farooq S, Deepa M . Prevalence of fibrocalculous pancreatic diabetes in Chennai in South India. JOP. 2008; 9(4):489-92. View

4.
Mohan V, Barman K, Rajan V, Chari S, Deepa R . Natural history of endocrine failure in tropical chronic pancreatitis: a longitudinal follow-up study. J Gastroenterol Hepatol. 2005; 20(12):1927-34. DOI: 10.1111/j.1440-1746.2005.04068.x. View

5.
Sahoo S, Zaidi G, Vipin V, Chapla A, Thomas N, Yu L . Heterogeneity in the aetiology of diabetes mellitus in young adults: A prospective study from north India. Indian J Med Res. 2019; 149(4):479-488. PMC: 6676834. DOI: 10.4103/ijmr.IJMR_1004_17. View