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S100A9-targeted Tobacco Mosaic Virus Nanoparticles Exhibit High Specificity Toward Atherosclerotic Lesions in ApoE Mice

Overview

Overview

Journal J Mater Chem B

Publisher Royal Society of Chemistry

Specialty Biomedical Engineering

Date 2020 Apr 8

PMID 32255046

Citations 10

Authors

Authors

Jooneon Park

HuiYun Gao

Yunmei Wang

He Hu

Daniel I Simon

Nicole F Steinmetz

Affiliations

Affiliations

Soon will be listed here.

Abstract

We integrate a biocompatible plant virus-based nanotechnology (tobacco mosaic virus, TMV) with S100A9-targeting peptides for its application in imaging and diagnosis of atherosclerosis. S100A9-targeted TMV nanoparticles exhibit remarkable specificity to S100A9 and targeting of atherosclerosis lesions in ApoE mice.

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