Rational Design of FeO@C Nanoparticles for Simultaneous Bimodal Imaging and Chemo-photothermal Therapy in Vitro and in Vivo

Overview

Journal J Mater Chem B

Publisher Royal Society of Chemistry

Specialty Biomedical Engineering

Date 2020 Apr 8

PMID 32254603

Citations 4

Authors

Qinghe Han

Xiaodong Wang

Zhiqiang Sun

Xiaofei Xu

Longhai Jin

Lixin Qiao

Qinghai Yuan

Affiliations

Soon will be listed here.

Abstract

We report a facile strategy to fabricate well-dispersed FeO@C eccentric core-shell nanoparticles (NPs). The resulting FeO@C eccentric core-shell NPs possess a high payload of doxorubicin (DOX) for use as synergetic pH/near-infrared (NIR)-sensitive drug delivery vehicles, and were applied for dual-modal magnetic resonance imaging (MRI)/photoacoustic imaging (PAI) and synergistic photothermal cancer therapy in vitro and in vivo.

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