Antidepressant Use in a 3- to 12-Year Follow-up of Anxious Youth: Results from the CAMELS Trial

Overview

Journal Child Psychiatry Hum Dev

Specialties Pediatrics
Psychiatry

Date 2020 Apr 8

PMID 32253545

Citations 1

Authors

Elana R Kagan

Hannah E Frank

Lesley A Norris

Sophie A Palitz

Erika A Chiappini

Mark J Knepley

Margaret E Crane

Katherine E Phillips

Golda S Ginsburg

Courtney Keeton

Anne Marie Albano

John Piacentini

Tara Peris

Scott Compton

Dara Sakolsky

Boris Birmaher

Philip C Kendall

Affiliations

Soon will be listed here.

Abstract

The current study explored whether patient characteristics predicted patterns of antidepressant use (i.e., never used, single episode of use, or two or more episodes) in a naturalistic follow-up. Participants in the child/adolescent multimodal (CAMS) extended long-term study. (n = 318) indicated medication use over the course of eight follow-up visits, 3-12 years after receiving treatment in CAMS. 40.6% of participants reported never using an antidepressant during follow-up, 41.4% reported a single episode of antidepressant use, and 18.0% reported multiple episodes of antidepressant use. Greater baseline anxiety severity marginally predicted a single episode of antidepressant use; baseline depression severity predicted multiple episodes of use. Reasons for discontinuing antidepressants included perceived ineffectiveness (31.8%), side effects (25.5%), and improvement in symptoms (18.5%). Exploratory analyses examined predictors of medication use. Findings suggest that antidepressant use is common among anxious youth, as is discontinuation of antidepressant use. Clinical implications and future directions are discussed.

Citing Articles

Long-term use of antidepressants, mood stabilizers, and antipsychotics in pediatric patients with a focus on appropriate deprescribing.

Stutzman D Ment Health Clin. 2021; 11(6):320-333.

PMID: 34824957 PMC: 8582767. DOI: 10.9740/mhc.2021.11.320.

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