HIV Treatment Knowledge in the Context of "Treatment As Prevention" (TasP)

Overview

Journal AIDS Behav

Specialty Infectious Diseases

Date 2020 Apr 5

PMID 32246359

Citations 8

Authors

Margaret M Paschen-Wolff

Aimee N C Campbell

Susan Tross

Michael Castro

Hayley Berg

Sarah Braunstein

Christine Borges

Don Des Jarlais

Affiliations

Soon will be listed here.

Abstract

According to 2012 universal ART guidelines, as part of "treatment as prevention" (TasP), all people living with HIV (PLWH) should immediately initiate antiretroviral therapy post-diagnosis to facilitate viral suppression. PLWH who are virally suppressed have no risk of sexually transmitting HIV. This study used descriptive analysis of quantitative data (N = 99) and thematic analysis of qualitative interviews (n = 36) to compare participants recruited from a hospital-based detoxification (detox) unit, largely diagnosed with HIV pre-2012 (n = 63) vs. those recruited from public, urban sexual health clinics (SHCs), mainly diagnosed in 2012 or later (n = 36). Detox participants were significantly more knowledgeable than SHC participants about HIV treatment, except regarding TasP. SHC participants' desire for rapid linkage to care and ART initiation was in line with 2012 universal ART guidelines and TasP messaging regarding viral suppression. More targeted messaging to PLWH pre-2012 could ensure that all PLWH benefit from scientific advances in HIV treatment.

Citing Articles

Improving HIV testing, linkage, and retention in care among South African men through U = U messaging: A study protocol for two sequential hybrid type 1 effectiveness-implementation randomized controlled trials.

Medina-Marino A, Sibanda N, Putt M, Davey D, Smith P, Thirumurthy H PLoS One. 2024; 19(11):e0309905.

PMID: 39585844 PMC: 11588259. DOI: 10.1371/journal.pone.0309905.

Improving HIV testing, linkage, and retention in care among South African men through U=U messaging: A study protocol for two sequential hybrid type 1 effectiveness- implementation randomized controlled trials.

Medina-Marino A, Sibanda N, Putt M, Davey D, Smith P, Thirumurthy H Res Sq. 2023; .

PMID: 37886512 PMC: 10602079. DOI: 10.21203/rs.3.rs-3349696/v1.

MASI, a Smartphone App to Improve Treatment Adherence Among South African Adolescents and Young Adults With HIV: Protocol for a Pilot Randomized Controlled Trial.

Mulawa M, Hoare J, Knippler E, Mtukushe B, Matiwane M, Muessig K JMIR Res Protoc. 2023; 12:e47137.

PMID: 37725409 PMC: 10548319. DOI: 10.2196/47137.

Amplified HIV Transmission Risk Among People Living With HIV in Southeast Brazil.

Reis R, Antonini M, Sousa L, de Alencar Rocha K, Ferreira G, Vettore M J Assoc Nurses AIDS Care. 2023; 34(5):469-480.

PMID: 37565984 PMC: 10470434. DOI: 10.1097/JNC.0000000000000421.

Challenges to communicating the Undetectable equals Untransmittable (U=U) HIV prevention message: Healthcare provider perspectives.

Grace D, Stewart M, Blaque E, Ryu H, Anand P, Gaspar M PLoS One. 2022; 17(7):e0271607.

PMID: 35862361 PMC: 9302742. DOI: 10.1371/journal.pone.0271607.

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