Protective Effects of Luteolin on Nephrotoxicity Induced by Long-term Hyperglycaemia in Rats

Overview

Journal J Int Med Res

Publisher Sage Publications

Specialty General Medicine

Date 2020 Apr 4

PMID 32242458

Citations 17

Authors

Cui Xiong

Qilong Wu

Mingling Fang

Hui Li

Bin Chen

Tingting Chi

Affiliations

Soon will be listed here.

Citing Articles

Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases.

Lv J, Song X, Luo Z, Huang D, Xiao L, Zou K Front Pharmacol. 2025; 16:1535555.

PMID: 40012626 PMC: 11861102. DOI: 10.3389/fphar.2025.1535555.

Impact of Olive Oil Components on the Expression of Genes Related to Type 2 Diabetes Mellitus.

Munteanu C, Kotova P, Schwartz B Nutrients. 2025; 17(3).

PMID: 39940428 PMC: 11820997. DOI: 10.3390/nu17030570.

Therapeutic Potential of Luteolin for Diabetes Mellitus and Its Complications.

Chang X, Yue R Chin J Integr Med. 2024; .

PMID: 39302570 DOI: 10.1007/s11655-024-3917-z.

Dietary intake of luteolin is negatively associated with all-cause and cardiovascular mortality in chronic kidney disease patients.

Yao X, Zhou Z BMC Public Health. 2024; 24(1):2044.

PMID: 39080632 PMC: 11290116. DOI: 10.1186/s12889-024-19458-x.

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source.

Pradhan G, Kulkarni Y Curr Diabetes Rev. 2024; 21(1):e290224227537.

PMID: 38425118 DOI: 10.2174/0115733998285798240217084632.

References

Liu Y, Huang J, Zheng X, Yang X, Ding Y, Fang T . Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway. Sci Rep. 2017; 7(1):7877. PMC: 5554232. DOI: 10.1038/s41598-017-08204-6. View

Jha J, Thallas-Bonke V, Banal C, Gray S, Chow B, Ramm G . Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy. Diabetologia. 2015; 59(2):379-89. PMC: 6450410. DOI: 10.1007/s00125-015-3796-0. View

Keating S, van Diepen J, Riksen N, El-Osta A . Epigenetics in diabetic nephropathy, immunity and metabolism. Diabetologia. 2017; 61(1):6-20. PMC: 6448927. DOI: 10.1007/s00125-017-4490-1. View

Miean K, Mohamed S . Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J Agric Food Chem. 2001; 49(6):3106-12. DOI: 10.1021/jf000892m. View

Vleming L, Baelde J, Westendorp R, Daha M, van Es L, Bruijn J . The glomerular deposition of PAS positive material correlates with renal function in human kidney diseases. Clin Nephrol. 1997; 47(3):158-67. View

Wu L, Wang Q, Guo F, Ma X, Ji H, Liu F . MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARγ, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy. Sci Rep. 2016; 6:26072. PMC: 4869109. DOI: 10.1038/srep26072. View

Bertolotto M, Martegani A, Aiani L, Zappetti R, Cernic S, Cova M . Value of contrast-enhanced ultrasonography for detecting renal infarcts proven by contrast enhanced CT. A feasibility study. Eur Radiol. 2007; 18(2):376-83. DOI: 10.1007/s00330-007-0747-2. View

Reudelhuber T . Prorenin, Renin, and their receptor: moving targets. Hypertension. 2010; 55(5):1071-4. DOI: 10.1161/HYPERTENSIONAHA.108.120279. View

Nilsson A . Contrast-enhanced ultrasound of the kidneys. Eur Radiol. 2005; 14 Suppl 8:P104-9. View

10.

Hostetter T . Hyperfiltration and glomerulosclerosis. Semin Nephrol. 2003; 23(2):194-9. DOI: 10.1053/anep.2003.50017. View

11.

Wolf G . New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. Eur J Clin Invest. 2004; 34(12):785-96. DOI: 10.1111/j.1365-2362.2004.01429.x. View

12.

Xing L, Liu Q, Fu S, Li S, Yang L, Liu S . PTEN Inhibits High Glucose-Induced Phenotypic Transition in Podocytes. J Cell Biochem. 2015; 116(8):1776-84. DOI: 10.1002/jcb.25136. View

13.

Choi B, Lim D, Lee J, Gao S, Kwon D, Kim B . Luteolin suppresses cisplatin-induced apoptosis in auditory cells: possible mediation through induction of heme oxygenase-1 expression. J Med Food. 2008; 11(2):230-6. DOI: 10.1089/jmf.2007.591. View

14.

Bechtel W, McGoohan S, Zeisberg E, Muller G, Kalbacher H, Salant D . Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010; 16(5):544-50. PMC: 3106179. DOI: 10.1038/nm.2135. View

15.

Rooban B, Sasikala V, Devi V, Sahasranamam V, Abraham A . Prevention of selenite induced oxidative stress and cataractogenesis by luteolin isolated from Vitex negundo. Chem Biol Interact. 2012; 196(1-2):30-8. DOI: 10.1016/j.cbi.2012.01.005. View

16.

Wang J, Gao T, Wang F, Xue J, Ye H, Xie M . Luteolin improves myocardial cell glucolipid metabolism by inhibiting hypoxia inducible factor-1α expression in angiotensin II/hypoxia-induced hypertrophic H9c2 cells. Nutr Res. 2019; 65:63-70. DOI: 10.1016/j.nutres.2019.02.004. View

17.

McArthur C, Baxter G . Current and potential renal applications of contrast-enhanced ultrasound. Clin Radiol. 2012; 67(9):909-22. DOI: 10.1016/j.crad.2012.01.017. View

18.

Doublier S, Salvidio G, Lupia E, Ruotsalainen V, Verzola D, Deferrari G . Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes. 2003; 52(4):1023-30. DOI: 10.2337/diabetes.52.4.1023. View

19.

Wang Y, Li H, Song S . β-Arrestin 1/2 Aggravates Podocyte Apoptosis of Diabetic Nephropathy via Wnt/β-Catenin Pathway. Med Sci Monit. 2018; 24:1724-1732. PMC: 5881455. DOI: 10.12659/msm.905642. View

20.

Shinozaki Y, Furuichi K, Toyama T, Kitajima S, Hara A, Iwata Y . Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease. Kidney Int. 2017; 92(6):1356-1369. DOI: 10.1016/j.kint.2017.04.032. View