Platelet-Rich Fibrin in Coverage of Gingival Recession: A Systematic Review and Meta-Analysis

Overview

Journal Eur J Dent

Publisher Thieme

Specialty Dentistry

Date 2020 Mar 30

PMID 32221958

Citations 9

Authors

Miguel Augusto Riquelme Rodas

Bruna Luisa de Paula

Victor Fabrizio Cabrera Pazmino

Flavia Ferraz Dos Santos Lot Vieira

Joel Ferreira Santiago Junior

Elcia Maria Varize Silveira

Affiliations

Soon will be listed here.

Abstract

This systematic review and meta-analysis sought to evaluate the efficacy of platelet-rich fibrin (PRF) membranes versus subepithelial connective tissue grafts (SCTGs) in the coverage of Miller class I and II gingival recessions. After the inclusion and exclusion criteria were applied, the quality of seven articles (Cohen's Kappa = 0.9) was evaluated using the scale. The MEDLINE/PubMed, Cochrane, and Web of Science databases were consulted, and manual searches were performed in the most popular periodontics journals. The studies included considered a total of 122 patients, 203 surgical fields on which SCTGs were used, and 205 surgical fields on which PRF was used. The parameters analyzed were probing depth, clinical attachment level, gingival recession, and keratinized mucosa. The minimum follow-up period accepted was 6 months. A statistically significant difference between the SCTG and PRF groups was found only in the case of keratinized mucosa. However, gingival recession, clinical attachment level, and probing depth parameters in the PRF group were found to be statistically equal to those of the SCTG group (the gold standard) ( ≥0.05). PRF membranes were determined to be a promising alternative to autogenous gingival grafts in the treatment of Miller class I and II gingival recessions.

Citing Articles

Comparative evaluation of coronally advanced flap and semilunar coronally repositioned flap, using platelet-rich fibrin in Miller's Class I recession defects: A randomized clinical trial.

Saifi S, Gummaluri S, Rani A, Manjunath R J Indian Soc Periodontol. 2025; 28(3):360-367.

PMID: 39742057 PMC: 11684582. DOI: 10.4103/jisp.jisp_251_23.

Efficacy of autologous platelet concentrates for root coverage of Miller's Class I and II gingival recession defects: A systematic review and meta-analysis.

Yaghini J, Mogharehabed A, Feizi A, Yazdanfar F Dent Res J (Isfahan). 2024; 21:63.

PMID: 39735223 PMC: 11676317. DOI: 10.4103/drj.drj_437_22.

Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis.

Saleh W, Abdelhaleem M, Elmeadawy S BMC Oral Health. 2024; 24(1):1400.

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From Healing to Regeneration: A Comprehensive Review of the Efficacy of Platelet-Rich Fibrin in Periodontal Plastic Surgery Procedures.

Jamjoom A Cureus. 2024; 16(9):e69287.

PMID: 39268023 PMC: 11392565. DOI: 10.7759/cureus.69287.

The effect of platelet-rich fibrin (PRF) versus freeze-dried bone allograft (FDBA) used in alveolar ridge preservation on the peri-implant soft and hard tissues: a randomized clinical trial.

Azangookhiavi H, Habibzadeh S, Zahmatkesh H, Mellati E, Mosaddad S, Dadpour Y BMC Oral Health. 2024; 24(1):693.

PMID: 38877446 PMC: 11179368. DOI: 10.1186/s12903-024-04478-1.

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