Novel Genetic Variant of a Class B G Protein-Coupled Receptor Reveals a Role for Adrenomedullin in Human Fertility
Overview
Overview
Journal
ACS Pharmacol Transl Sci
Publisher
American Chemical Society
Specialty
Biochemistry
Date
2020 Mar 29
PMID
32219210
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Booe J, Walker C, Barwell J, Kuteyi G, Simms J, Jamaluddin M
. Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Mol Cell. 2015; 58(6):1040-52.
PMC: 4504005.
DOI: 10.1016/j.molcel.2015.04.018.
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2.
Kadmiel M, Fritz-Six K, Pacharne S, Richards G, Li M, Skerry T
. Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in mice. Mol Endocrinol. 2011; 25(7):1244-53.
PMC: 3125095.
DOI: 10.1210/me.2010-0400.
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3.
Matson B, Quinn K, Lessey B, Young S, Caron K
. Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis. Fertil Steril. 2018; 109(6):1072-1078.
PMC: 6015786.
DOI: 10.1016/j.fertnstert.2018.02.004.
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Mackie D, Al Mutairi F, Davis R, Kechele D, Nielsen N, Snyder J
. h mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. J Exp Med. 2018; 215(9):2339-2353.
PMC: 6122977.
DOI: 10.1084/jem.20180528.
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5.
Caron K, SMITHIES O
. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci U S A. 2001; 98(2):615-9.
PMC: 14636.
DOI: 10.1073/pnas.98.2.615.
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