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A Rare Colonic Metastasis Case from Hepatocellular Carcinoma

Overview
Specialty General Medicine
Date 2020 Mar 28
PMID 32215096
Citations 6
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Abstract

Background: Hepatocellularcarcinoma (HCC) metastasis include intrahepatic and extrahepatic metastasis. Similar to intrahepatic metastasis, extrahepatic metastases are not unusual in cases with HCC. However, colonic metastasis is infrequent.

Case Report: We describe a clinical case, he was diagnosed with HCC a year ago, treated with TACE (transarterialchemoembolisation), re-examined with abdominal pain and defecation disorder. The tests such as CT scan, colorectal endoscopy, fine needle aspiration (FNA) revealed secondary metastatic lesion of HCC in sigmoid colon. This is the first gastrointestinal (GI) tract metastatic we have encountered.

Conclusion: HCC metastases of the colon are rare, especially cases of hematogenous spread. The prognosis of these patients is often very critical. Indications for surgical removal of the lesion may be used if the general situation of patient is acceptable.

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References
1.
Chu P, Ishizawa S, Wu E, Weiss L . Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein. Am J Surg Pathol. 2002; 26(8):978-88. DOI: 10.1097/00000478-200208000-00002. View

2.
Fan Z, van de Rijn M, Montgomery K, Rouse R . Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections. Mod Pathol. 2003; 16(2):137-44. DOI: 10.1097/01.MP.0000052103.13730.20. View

3.
Si M, Amersi F, Golish S, Ortiz J, Zaky J, Finklestein D . Prevalence of metastases in hepatocellular carcinoma: risk factors and impact on survival. Am Surg. 2003; 69(10):879-85. View

4.
Uka K, Aikata H, Takaki S, Shirakawa H, Jeong S, Yamashina K . Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma. World J Gastroenterol. 2007; 13(3):414-20. PMC: 4065897. DOI: 10.3748/wjg.v13.i3.414. View

5.
Bray F, Ferlay J, Soerjomataram I, Siegel R, Torre L, Jemal A . Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68(6):394-424. DOI: 10.3322/caac.21492. View