Household Airborne Endotoxin Associated with Asthma and Allergy in Elementary School-age Children: a Case-control Study in Kaohsiung, Taiwan

Overview

Journal Environ Sci Pollut Res Int

Publisher Springer

Specialties Environmental Health
Toxicology

Date 2020 Mar 27

PMID 32212084

Citations 2

Authors

Yu-Chuan Yen

Chun-Yuh Yang

Tsu-Nai Wang

Pei-Chun Yen

Chi-Kung Ho

Kristina D Mena

Tzu-Chi Lee

Kang-Shin Chen

Yuan-Chung Lin

Pei-Shih Chen

Affiliations

Soon will be listed here.

Abstract

To evaluate the association between the presence of asthma and allergy, and airborne endotoxin in homes of school-age children in Kaohsiung City, Taiwan, with a case-control study design by matching the age and class exposure. Data collection of home visits included an interviewer-administered questionnaire and air sampling of participants' homes for endotoxin, bacteria, and fungi, as well as temperature and relative humidity measurements. Endotoxin was detected in all air samples with a median value of 0.67 EU m. In the adjusted logistic regression model, household airborne endotoxin was associated with higher prevalence of asthma and allergy; OR = 4.88 (95% CI 1.16-20.55) for Q3 (between 0.67 and 1.97 EU m ) vs. Q1 (< 0.31 EU m ), with statistical significance. Airborne fungi were associated with higher prevalence of asthma and allergy; OR = 4.47 (95% CI 1.13-17.69) for Q3 (between 314 and 699 CFU m ) vs. Q1 (< 159 CFU m ) in adjusted logistic regression models. Airborne endotoxin and fungi were significantly associated with children's asthma and allergy.

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