Systematic Review and Meta: Analysis of Aortic Graft Infections Following Abdominal Aortic Aneurysm Repair

Overview

Journal Int J Vasc Med

Publisher Wiley

Specialty Cardiology & Vascular Diseases

Date 2020 Mar 25

PMID 32206352

Citations 9

Authors

O S Niaz

A Rao

D Carey

J R Refson

A Abidia

P Somaiya

Affiliations

Soon will be listed here.

Abstract

Methods: Data was collected between July and August 2018. A full HDAS search was conducted on the following databases: MEDLINE, EMBASE, CINAHL, and PUBMED. Meta-analysis was conducted using RevMan 5 software.

Results: 1,365 patient outcomes were assessed (10 cohort studies and 12 comparative studies). The most common treatment was in situ replacement of the graft (ISR) followed by extra-anatomical replacement (EAR). Various grafts were used for ISR, such as fresh/cryopreserved allograft, venous graft, and prosthetic grafts. No graft material was shown to be superior. Axillobifemoral graft was the commonest type of EAR used. In the majority of cohort studies, ISR was the main treatment for AGI. There was no significant difference in the overall mortality rate (ISR = 70/176 vs. EAR = 70/176 vs. EAR = 0.87). Graft occlusion rate was significantly lower in the ISR group vs. the EAR group ( = 70/176 vs. EAR = 70/176 vs. EAR = 0.87). Graft occlusion rate was significantly lower in the ISR group vs. the EAR group ( = 70/176 vs. EAR = 70/176 vs. EAR = 0.87). Graft occlusion rate was significantly lower in the ISR group vs. the EAR group (. In situ replacement is the preferred method of treatment as it had lower rates of occlusion. Further strong evidence is required, such as a multicentre trial to establish a management pathway for the condition.

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