Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2020 Mar 22

PMID 32197494

Citations 56

Authors

Ana Dobrincic

Sandra Balbino

Zoran Zoric

Sandra Pedisic

Danijela Bursac Kovacevic

Ivona Elez Garofulic

Verica Dragovic-Uzelac

Affiliations

Soon will be listed here.

Abstract

Over the years, brown algae bioactive polysaccharides laminarin, alginate and fucoidan have been isolated and used in functional foods, cosmeceutical and pharmaceutical industries. The extraction process of these polysaccharides includes several complex and time-consuming steps and the correct adjustment of extraction parameters (e.g., time, temperature, power, pressure, solvent and sample to solvent ratio) greatly influences the yield, physical, chemical and biochemical properties as well as their biological activities. This review includes the most recent conventional procedures for brown algae polysaccharides extraction along with advanced extraction techniques (microwave-assisted extraction, ultrasound assisted extraction, pressurized liquid extraction and enzymes assisted extraction) which can effectively improve extraction process. The influence of these extraction techniques and their individual parameters on yield, chemical structure and biological activities from the most current literature is discussed, along with their potential for commercial applications as bioactive compounds and drug delivery systems.

Citing Articles

Marine-Derived Polysaccharides and Their Potential Health Benefits in Nutraceutical Applications.

Carrasqueira J, Bernardino S, Bernardino R, Afonso C Mar Drugs. 2025; 23(2).

PMID: 39997184 PMC: 11857343. DOI: 10.3390/md23020060.

Sustainable and biocompatible hybrid materials-based sulfated polysaccharides for biomedical applications: a review.

Alfinaikh R, Alamry K, Hussein M RSC Adv. 2025; 15(6):4708-4767.

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Unlocking the Therapeutic Potential of Algae-Derived Compounds in Hematological Malignancies.

Vujovic T, Paradzik T, Babic Brcic S, Piva R Cancers (Basel). 2025; 17(2).

PMID: 39858100 PMC: 11763723. DOI: 10.3390/cancers17020318.

Antimicrobial Activities of Polysaccharide-Rich Extracts from the Irish Seaweed , Generated Using Green and Conventional Extraction Technologies, Against Foodborne Pathogens.

McGurrin A, Suchintita Das R, Soro A, Maguire J, Florez Fernandez N, Dominguez H Mar Drugs. 2025; 23(1).

PMID: 39852548 PMC: 11767211. DOI: 10.3390/md23010046.

A Comparative Review of Alternative Fucoidan Extraction Techniques from Seaweed.

Chadwick M, Carvalho L, Vanegas C, Dimartino S Mar Drugs. 2025; 23(1).

PMID: 39852529 PMC: 11766506. DOI: 10.3390/md23010027.

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