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Mitochondrial GSDMD Pores DAMPen Pyroptosis

Overview
Journal Immunity
Publisher Cell Press
Specialty Allergy & Immunology
Date 2020 Mar 19
PMID 32187511
Citations 20
Authors
Katherine C Barnett
Jenny P-Y Ting
Affiliations
Soon will be listed here.
Abstract

Noncanoncial inflammasome activation by cytosolic lipopolysaccharide (LPS) causes pyroptotic cell death facilitated by gasdermin D (GSDMD) pore formation. In this issue of Immunity, Huang et al. describe how cytosolic LPS in endothelial cells does not cause cell death but restrains endothelial cell proliferation.

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References
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