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Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature

Overview
Publisher Wiley
Specialty Oncology
Date 2020 Mar 18
PMID 32181035
Citations 8
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Abstract

Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females.

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References
1.
Gibbs Jr B, ROE R, THOMAS D . Malignant cystosarcoma phyllodes in a pre-pubertal female. Ann Surg. 1968; 167(2):229-31. PMC: 1387408. DOI: 10.1097/00000658-196802000-00011. View

2.
RISSANEN P, HOLSTI P . A retrospective study of sarcoma of the breast and the results of treatment. Oncology. 1968; 22(4):258-68. DOI: 10.1159/000224457. View

3.
Teo J, Cheong C, Wong C . Low local recurrence rates in young Asian patients with phyllodes tumours: less is more. ANZ J Surg. 2012; 82(5):325-8. DOI: 10.1111/j.1445-2197.2012.06045.x. View

4.
Macdonald O, Lee C, Tward J, Chappel C, Gaffney D . Malignant phyllodes tumor of the female breast: association of primary therapy with cause-specific survival from the Surveillance, Epidemiology, and End Results (SEER) program. Cancer. 2006; 107(9):2127-33. DOI: 10.1002/cncr.22228. View

5.
Grigioni W, Santini D, Grassigli A, Taffurelli M, Milani M, Vanzo M . A clinico-pathologic study of cystosarcoma phyllodes. Twenty cases report. Arch Anat Cytol Pathol. 1982; 30(5-6):303-6. View