Bioactivity and Physico-Chemical Properties of Dental Composites Functionalized with Nano- Vs. Micro-Sized Bioactive Glass

Overview

Journal J Clin Med

Specialty General Medicine

Date 2020 Mar 18

PMID 32178372

Citations 15

Authors

Reto Odermatt

Matej Par

Dirk Mohn

Daniel B Wiedemeier

Thomas Attin

Tobias T Taubock

Affiliations

Soon will be listed here.

Abstract

Bioactive resin composites can contribute to the prevention of secondary caries, which is one of the main reasons for failure of contemporary dental restorations. This study investigated the effect of particle size of bioactive glass 45S5 on chemical and physical composite properties. Four experimental composites were prepared by admixing the following fillers into a commercial flowable composite: (1) 15 wt% of micro-sized bioactive glass, (2) 15 wt% of nano-sized bioactive glass, (3) a combination of micro- (7.5 wt%) and nano-sized (7.5 wt%) bioactive glass, and (4) 15 wt% of micro-sized inert barium glass. Hydroxyapatite precipitation and pH rise in phosphate-buffered saline were evaluated during 28 days. Degree of conversion and Knoop microhardness were measured 24 h after specimen preparation and after 28 days of phosphate-buffered saline immersion. Data were analyzed using non-parametric statistics (Kruskal-Wallis and Wilcoxon tests) at an overall level of significance of 5%. Downsizing the bioactive glass particles from micro- to nano-size considerably improved their capability to increase pH. The effect of nano-sized bioactive glass on degree of conversion and Knoop microhardness was similar to that of micro-sized bioactive glass. Composites containing nano-sized bioactive glass formed a more uniform hydroxyapatite layer after phosphate-buffered saline immersion than composites containing exclusively micro-sized particles. Partial replacement of nano- by micro-sized bioactive glass in the hybrid composite did not impair its reactivity, degree of conversion ( > 0.05), and Knoop microhardness ( > 0.05). It is concluded that downsizing bioactive glass particles to nano-size improves the alkalizing potential of experimental composites with no negative effects on their fundamental properties.

Citing Articles

A review of new generation of dental restorative resin composites with antibacterial, remineralizing and self-healing capabilities.

Zhang J, Yang Y, Chen Y, Chen X, Li A, Wang J Discov Nano. 2024; 19(1):189.

PMID: 39570468 PMC: 11582236. DOI: 10.1186/s11671-024-04151-0.

Water-Induced Changes in Experimental Resin Composites Functionalized with Conventional (45S5) and Customized Bioactive Glass.

Muradbegovic A, Par M, Panduric V, Zugec P, Taubock T, Attin T J Funct Biomater. 2023; 14(6).

PMID: 37367262 PMC: 10298865. DOI: 10.3390/jfb14060298.

Ceramic Nanomaterials in Caries Prevention: A Narrative Review.

Nizami M, Xu V, Yin I, Lung C, Niu J, Chu C Nanomaterials (Basel). 2022; 12(24).

PMID: 36558269 PMC: 9786898. DOI: 10.3390/nano12244416.

A Narrative Review of Bioactive Glass-Loaded Dental Resin Composites.

Yun J, Burrow M, Matinlinna J, Wang Y, Tsoi J J Funct Biomater. 2022; 13(4).

PMID: 36412849 PMC: 9680275. DOI: 10.3390/jfb13040208.

Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives.

Kreutz M, Kreutz C, Kanzow P, Taubock T, Burrer P, Noll C Nanomaterials (Basel). 2022; 12(21).

PMID: 36364638 PMC: 9694625. DOI: 10.3390/nano12213862.

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