Health Related Quality of Life in Japanese Patients with Localized Prostate Cancer: Comparative Retrospective Study of Robot-Assisted Laparoscopic Radical Prostatectomy Versus Radiation Therapy

Overview

Journal Yonago Acta Med

Specialty General Medicine

Date 2020 Mar 12

PMID 32158334

Citations 2

Authors

Yoko Miyoshi

Shuichi Morizane

Masashi Honda

Katsuya Hikita

Hideto Iwamoto

Tetsuya Yumioka

Yusuke Kimura

Shin-Ichi Yoshioka

Atsushi Takenaka

Affiliations

Soon will be listed here.

Abstract

Background: Radical prostatectomy and radiotherapy are standard treatments for localized prostate cancer. When making decisions about treatment, it is important to not only consider medical information such as the patient's age, performance status, and complications, but also the impact on quality of life (QOL) after treatment.

Methods: Patients with localized prostate cancer receiving RARP or radiotherapy at Tottori University Hospital between October 2010 and December 2014 were enrolled in a retrospective observational study with follow-up for 24 months to December 2016. The Medical Outcome Study 8-Item Short-Form Health Survey was performed before treatment and 1, 3, 6, 12, and 24 months post-treatment.

Results: Complete responses to the questionnaire were obtained from 154/227 patients receiving RARP, 41/67 patients receiving intensity-modulated radiation therapy, 35/82 patients receiving low dose rate brachytherapy, and 18/28 patients given low dose rate brachytherapy plus external beam radiation therapy. The median physical component summary score of the Medical Outcome Study 8-Item Short-Form Health Survey was significantly lower at 1 month after prostatectomy than radiotherapy, but was similar for both treatments at 3 months, and was significantly higher at 6, 12 and 24 months after prostatectomy. The median mental component summary score was also significantly lower in the prostatectomy group at 1 month, but not from 3 months onwards.

Conclusion: Our study suggested that HRQOL was inferior at 1 month after RARP, however, recovered at 3 months after RARP and was better than after radiotherapy at 6, 12, and 24 months.

Citing Articles

The effect of the type of surgery performed due to prostate cancer on preoperative patient anxiety, a prospective study.

Ergani B, Ozbilen M, Yalcin M, Boyacioglu H, Ilbey Y Am J Clin Exp Urol. 2021; 9(1):88-95.

PMID: 33816697 PMC: 8012827.

Changes in sexual function and serum testosterone levels in patients with prostate cancer after image-guided proton therapy.

Hattori Y, Iwata H, Nakajima K, Nomura K, Hayashi K, Toshito T J Radiat Res. 2021; 62(3):517-524.

PMID: 33675355 PMC: 8127670. DOI: 10.1093/jrr/rrab002.

References

Song L, Chen R, Bensen J, Knafl G, Nielsen M, Farnan L . Who makes the decision regarding the treatment of clinically localized prostate cancer--the patient or physician?: results from a population-based study. Cancer. 2012; 119(2):421-8. PMC: 7671233. DOI: 10.1002/cncr.27738. View

Davis J, Kuban D, LYNCH D, Schellhammer P . Quality of life after treatment for localized prostate cancer: differences based on treatment modality. J Urol. 2001; 166(3):947-52. View

Ohashi T, Yorozu A, Saito S, Tanaka N, Katayama N, Kojima S . Urinary and Rectal Toxicity Profiles After Permanent Iodine-125 Implant Brachytherapy in Japanese Men: Nationwide J-POPS Multi-institutional Prospective Cohort Study. Int J Radiat Oncol Biol Phys. 2015; 93(1):141-9. DOI: 10.1016/j.ijrobp.2015.05.014. View

Murray L, Henry A, Hoskin P, Siebert F, Venselaar J . Second primary cancers after radiation for prostate cancer: a systematic review of the clinical data and impact of treatment technique. Radiother Oncol. 2014; 110(2):213-28. PMC: 3988985. DOI: 10.1016/j.radonc.2013.12.012. View

El Douaihy Y, Sooriakumaran P, Agarwal M, Srivastava A, Grover S, Mudaliar K . A cohort study investigating patient expectations and satisfaction outcomes in men undergoing robotic assisted radical prostatectomy. Int Urol Nephrol. 2010; 43(2):405-15. DOI: 10.1007/s11255-010-9817-5. View

Wallerstedt A, Nyberg T, Carlsson S, Thorsteinsdottir T, Stranne J, Tyritzis S . Quality of Life After Open Radical Prostatectomy Compared with Robot-assisted Radical Prostatectomy. Eur Urol Focus. 2018; 5(3):389-398. DOI: 10.1016/j.euf.2017.12.010. View

Fukuhara S, Ware Jr J, Kosinski M, Wada S, Gandek B . Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol. 1998; 51(11):1045-53. DOI: 10.1016/s0895-4356(98)00096-1. View

Akakura K, ISAKA S, Akimoto S, Ito H, Okada K, Hachiya T . Long-term results of a randomized trial for the treatment of Stages B2 and C prostate cancer: radical prostatectomy versus external beam radiation therapy with a common endocrine therapy in both modalities. Urology. 1999; 54(2):313-8. DOI: 10.1016/s0090-4295(99)00106-5. View

Sato M, Mori T, Shirai S, Kishi K, Inagaki T, Hara I . High-dose-rate brachytherapy of a single implant with two fractions combined with external beam radiotherapy for hormone-naive prostate cancer. Int J Radiat Oncol Biol Phys. 2008; 72(4):1002-9. DOI: 10.1016/j.ijrobp.2008.02.055. View

10.

Kakehi Y, Sugimoto M, Taoka R . Evidenced-based clinical practice guideline for prostate cancer (summary: Japanese Urological Association, 2016 edition). Int J Urol. 2017; 24(9):648-666. DOI: 10.1111/iju.13380. View

11.

Mohammad Jafri S, Nguyen L, Sirls L . Recovery of urinary function after robotic-assisted laparoscopic prostatectomy versus radical perineal prostatectomy for early-stage prostate cancer. Int Urol Nephrol. 2018; 50(12):2187-2191. DOI: 10.1007/s11255-018-2013-8. View

12.

Hashine K, Numata K, Koizumi T, Azuma K, Sumiyoshi Y . [Health-related quality of life after radical prostatectomy or radiotherapy]. Nihon Hinyokika Gakkai Zasshi. 2005; 96(4):495-502. DOI: 10.5980/jpnjurol1989.96.495. View

13.

Potosky A, Legler J, Albertsen P, Stanford J, Gilliland F, Hamilton A . Health outcomes after prostatectomy or radiotherapy for prostate cancer: results from the Prostate Cancer Outcomes Study. J Natl Cancer Inst. 2000; 92(19):1582-92. DOI: 10.1093/jnci/92.19.1582. View

14.

Miyake H, Miyazaki A, Furukawa J, Hinata N, Fujisawa M . Prospective assessment of time-dependent changes in quality of life of Japanese patients with prostate cancer following robot-assisted radical prostatectomy. J Robot Surg. 2016; 10(3):201-7. DOI: 10.1007/s11701-016-0565-0. View

15.

Ficarra V, Novara G, Ahlering T, Costello A, Eastham J, Graefen M . Systematic review and meta-analysis of studies reporting potency rates after robot-assisted radical prostatectomy. Eur Urol. 2012; 62(3):418-30. DOI: 10.1016/j.eururo.2012.05.046. View

16.

Litwin M, Hays R, Fink A, Ganz P, Leake B, Leach G . Quality-of-life outcomes in men treated for localized prostate cancer. JAMA. 1995; 273(2):129-35. DOI: 10.1001/jama.273.2.129. View

17.

Lubeck D, Litwin M, Henning J, Stoddard M, Flanders S, Carroll P . Changes in health-related quality of life in the first year after treatment for prostate cancer: results from CaPSURE. Urology. 1999; 53(1):180-6. DOI: 10.1016/s0090-4295(98)00408-7. View

18.

Budaus L, Bolla M, Bossi A, Cozzarini C, Crook J, Widmark A . Functional outcomes and complications following radiation therapy for prostate cancer: a critical analysis of the literature. Eur Urol. 2011; 61(1):112-27. DOI: 10.1016/j.eururo.2011.09.027. View

19.

McCammon K, Kolm P, Main B, Schellhammer P . Comparative quality-of-life analysis after radical prostatectomy or external beam radiation for localized prostate cancer. Urology. 1999; 54(3):509-16. DOI: 10.1016/s0090-4295(99)00163-6. View

20.

Chen R, Basak R, Meyer A, Kuo T, Carpenter W, Agans R . Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer. JAMA. 2017; 317(11):1141-1150. PMC: 6284802. DOI: 10.1001/jama.2017.1652. View