» Articles » PMID: 32151049

(Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer

Overview
Publisher MDPI
Specialty Chemistry
Date 2020 Mar 11
PMID 32151049
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

The role of nuclear medicine in the management of oncological patients has expanded during last two decades. The number of radiopharmaceuticals contributing to the realization of theranostics/radiotheranostics in the context of personalized medicine is increasing. This review is focused on the examples of targeted (radio)pharmaceuticals for the imaging and therapy of neuroendocrine neoplasms (NENs), prostate cancer, and breast cancer. These examples strongly demonstrate the tendency of nuclear medicine development towards personalized medicine.

Citing Articles

Future Prospect of Low-Molecular-Weight Prostate-Specific Membrane Antigen Radioisotopes Labeled as Theranostic Agents for Metastatic Castration-Resistant Prostate Cancer.

Ismuha R, Ritawidya R, Daruwati I, Muchtaridi M Molecules. 2025; 29(24.

PMID: 39770150 PMC: 11679579. DOI: 10.3390/molecules29246062.


Unveiling the Potential of Prostate-Specific Membrane Antigen for Precision Diagnosis and Therapy of Prostate Cancer: A Radiopharmaceutical Perspective.

Hassan H, Othman M, Ashhar Z, Abdul Razak H, Ahmad Saad F Malays J Med Sci. 2024; 31(4):213-217.

PMID: 39247120 PMC: 11377010. DOI: 10.21315/mjms2024.31.4.17.


The emerging role and mechanism of HMGA2 in breast cancer.

Ma Q, Ye S, Liu H, Zhao Y, Zhang W J Cancer Res Clin Oncol. 2024; 150(5):259.

PMID: 38753081 PMC: 11098884. DOI: 10.1007/s00432-024-05785-4.


Predicting [Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling.

Siebinga H, de Wit-van der Veen B, Beijnen J, Stokkel M, Dorlo T, Huitema A EJNMMI Phys. 2023; 10(1):48.

PMID: 37615812 PMC: 10449733. DOI: 10.1186/s40658-023-00565-4.

References
1.
Balogova S, Talbot J, Nataf V, Michaud L, Huchet V, Kerrou K . 18F-fluorodihydroxyphenylalanine vs other radiopharmaceuticals for imaging neuroendocrine tumours according to their type. Eur J Nucl Med Mol Imaging. 2013; 40(6):943-66. PMC: 3644207. DOI: 10.1007/s00259-013-2342-x. View

2.
Bouchelouche K, Choyke P . Prostate-specific membrane antigen positron emission tomography in prostate cancer: a step toward personalized medicine. Curr Opin Oncol. 2016; 28(3):216-21. PMC: 5515231. DOI: 10.1097/CCO.0000000000000277. View

3.
Blaickner M, Baum R . Relevance of PET for pretherapeutic prediction of doses in peptide receptor radionuclide therapy. PET Clin. 2014; 9(1):99-112. DOI: 10.1016/j.cpet.2013.08.014. View

4.
Haug A, Cindea-Drimus R, Auernhammer C, Reincke M, Beuschlein F, Wangler B . Neuroendocrine tumor recurrence: diagnosis with 68Ga-DOTATATE PET/CT. Radiology. 2013; 270(2):517-25. DOI: 10.1148/radiol.13122501. View

5.
Sandstrom M, Lindskog K, Velikyan I, Wennborg A, Feldwisch J, Sandberg D . Biodistribution and Radiation Dosimetry of the Anti-HER2 Affibody Molecule 68Ga-ABY-025 in Breast Cancer Patients. J Nucl Med. 2016; 57(6):867-71. DOI: 10.2967/jnumed.115.169342. View