Practical Synthesis of Ethynyl(phenyl)-λ-Iodane Using Calcium Carbide As an Ethynyl Group Source

Overview

Journal Front Chem

Specialty Chemistry

Date 2020 Mar 3

PMID 32117863

Citations 1

Authors

Takahiro Hashishin

Taisei Osawa

Kazunori Miyamoto

Masanobu Uchiyama

Affiliations

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Abstract

Stannylation of calcium carbide followed by Sn-hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-λ-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions.

Citing Articles

Recent Progress in Synthetic Applications of Hypervalent Iodine(III) Reagents.

Yoshimura A, Zhdankin V Chem Rev. 2024; 124(19):11108-11186.

PMID: 39269928 PMC: 11468727. DOI: 10.1021/acs.chemrev.4c00303.

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