Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
Overview
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Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.
Demir H, Ekim M, Ozgul E, Davarci S, Baykara M GMS Ophthalmol Cases. 2024; 14:Doc03.
PMID: 38774401 PMC: 11106631. DOI: 10.3205/oc000235.
Choroidal Metastasis as the Initial Presentation of Rectal Adenocarcinoma.
Amisha F, Patel T, Biyani S, Saluja P, Gautam N, Kakadia S Eur J Case Rep Intern Med. 2022; 8(12):003059.
PMID: 35059344 PMC: 8765696. DOI: 10.12890/2021_003059.
Role of Metastasis Suppressor KAI1/CD82 in Different Cancers.
Yan W, Huang J, Zhang Q, Zhang J J Oncol. 2021; 2021:9924473.
PMID: 34306081 PMC: 8285166. DOI: 10.1155/2021/9924473.