Pediatric Thyroid Cancer in Europe: An Overdiagnosed Condition? A Literature Review

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2020 Feb 26

PMID 32092888

Citations 10

Authors

Andreea-Ioana Stefan

Andra Piciu

Alexandru Mester

Dragos Apostu

Marius Badan

Claudiu-Iulian Badulescu

Affiliations

Soon will be listed here.

Abstract

Thyroid neoplastic pathology is the most common form of cancer associated with radiation exposure. The most common histopathological type of thyroid carcinoma is the differentiated thyroid cancer (these include papillary and follicular type), which represents over 90% of all cases, especially affecting girls rather than boys. Although patients are diagnosed in advanced stages as compared to adults, the prognosis of the disease is very good, with a 30-year survival rate of over 95% but post-therapeutic morbidity remains quite high. The treatment is based in particular on the therapeutic guidelines for adults, but as children have some histopathological and genetic characteristics of thyroid cancer, as well as different initial clinical presentations, we decided to review the literature on this pathology among the pediatric population, focusing on cases in Europe. The major interest is the impact of the Chernobyl accident.

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