[Investigation of Laryngopharyngeal Reflux Prevalence and Risk Factors in Otolaryngology]

Overview

Journal Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

Specialty Otorhinolaryngology

Date 2020 Feb 23

PMID 32086894

Citations 4

Authors

Y G Wang

Y H Guo

C F Li

J L Zhu

Y Y Chi

Y X Zhao

L H Zhang

Affiliations

Soon will be listed here.

Abstract

To investigate the prevalence and related risk factors of laryngopharyngeal reflux in otolaryngology. During January 2019 to March 2019, the inpatients in otolaryngology were investigated by the questionnaire of reflux symptom index scale and the laryngopharyngeal reflux related risk factors were analyzed. Among the 227 patients, 33 patients with suspected LPR contained 19 patients（20.7%） of 92 patients in the laryngopharyngeal group, 10 patients（16.1%） of 62 patients in the nasal group, and 4 patients（5.5%） of 73 patients in the ear group. LPR prevalence in the laryngopharyngeal group was statistically different from that in the ear group（<0.05）. Univariate logistic regression analysis showed that age, gender, smoking, drinking and BMI were risk factors of LPR（<0.01）. Multivariate logistic regression analysis indicated that BMI was an independent risk factor of LPR（<0.01）. LPR had a high prevalence rate in otolaryngology related diseases, and appropriate synergistic anti-LPR treatment could be carried out while treating otolaryngology related diseases.

Citing Articles

Correlation Between Refractory Laryngopharyngeal Reflux Disease and Symptoms of Anxiety and Depression.

Huang F, Liao Q, Gan X, Wen W Neuropsychiatr Dis Treat. 2022; 18:925-932.

PMID: 35502360 PMC: 9056093. DOI: 10.2147/NDT.S349933.

The Association between Free Sugars Consumption and Laryngopharyngeal Reflux: A Cross-Sectional Study among Chinese Adolescents.

Li F, Lin Q, Yang Q, Xi Y, Liu H, Luo J Nutrients. 2021; 13(9).

PMID: 34578890 PMC: 8468888. DOI: 10.3390/nu13093012.

[An epidemiological survey of laryngopharyngeal refux disease in otorhinolaryngology head and neck surgery clinics in Chongqing area].

Peng Y, Xu D, Liu X, He D, Wei L, Xiong J Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021; 35(4):351-354.

PMID: 33794636 PMC: 10128448. DOI: 10.13201/j.issn.2096-7993.2021.04.015.

[Risk factors affecting the surgical outcome of severe tracheal stenosis].

He T, Zhu W, Jiang Y, Chen P, Cai Q Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021; 35(3):238-241.

PMID: 33794609 PMC: 10128249. DOI: 10.13201/j.issn.2096-7993.2021.03.010.

References

Farrokhi F, Vaezi M . Extra-esophageal manifestations of gastroesophageal reflux. Oral Dis. 2007; 13(4):349-59. DOI: 10.1111/j.1601-0825.2007.01380.x. View

Abdel-aziz M, El-Fattah A, Abdalla A . Clinical evaluation of pepsin for laryngopharyngeal reflux in children with otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2013; 77(10):1765-70. DOI: 10.1016/j.ijporl.2013.08.014. View

Fisichella P . Hoarseness and laryngopharyngeal reflux. JAMA. 2015; 313(18):1853-4. DOI: 10.1001/jama.2014.17969. View

Hallan A, Bomme M, Hveem K, Moller-Hansen J, Ness-Jensen E . Risk factors on the development of new-onset gastroesophageal reflux symptoms. A population-based prospective cohort study: the HUNT study. Am J Gastroenterol. 2015; 110(3):393-400. DOI: 10.1038/ajg.2015.18. View

Lee Y, Choi S, Son Y, Park Y, Kim S, Nam S . Prospective, observational study using rabeprazole in 455 patients with laryngopharyngeal reflux disease. Eur Arch Otorhinolaryngol. 2011; 268(6):863-9. DOI: 10.1007/s00405-010-1475-9. View

Vossoughinia H, Salari M, Amirmajdi E, Saadatnia H, Abedini S, Shariati A . An epidemiological study of gastroesophageal reflux disease and related risk factors in urban population of mashhad, iran. Iran Red Crescent Med J. 2015; 16(12):e15832. PMC: 4341324. DOI: 10.5812/ircmj.15832. View

Wu J, Mui L, Cheung C, Chan Y, Jao-Yiu Sung J . Obesity is associated with increased transient lower esophageal sphincter relaxation. Gastroenterology. 2007; 132(3):883-9. DOI: 10.1053/j.gastro.2006.12.032. View

Kamani T, Penney S, Mitra I, Pothula V . The prevalence of laryngopharyngeal reflux in the English population. Eur Arch Otorhinolaryngol. 2012; 269(10):2219-25. DOI: 10.1007/s00405-012-2028-1. View

Li X, Li J, Zhang S, Zhang Y, Qi Z, Niu R . [A preliminary study on the relationship between laryngopharyngeal reflux and chronic rhinosinusitis]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018; 31(23):1828-1832. DOI: 10.13201/j.issn.1001-1781.2017.23.012. View

10.

Pincus R, Kim H, Silvers S, Gold S . A study of the link between gastric reflux and chronic sinusitis in adults. Ear Nose Throat J. 2006; 85(3):174-8. View

11.

Song J, Kown S, Kim E, Lee Y, Kim B, Chae S . Mucosal expression of ENaC and AQP in experimental otitis media induced by Eustachian tube obstruction. Int J Pediatr Otorhinolaryngol. 2009; 73(11):1589-93. DOI: 10.1016/j.ijporl.2009.08.011. View

12.

Ozdek A, Yalinay Cirak M, Samim E, Bayiz U, Asim Safak M, Turet S . A possible role of Helicobacter pylori in chronic rhinosinusitis: a preliminary report. Laryngoscope. 2003; 113(4):679-82. DOI: 10.1097/00005537-200304000-00018. View

13.

Belafsky P, Postma G, Koufman J . Validity and reliability of the reflux symptom index (RSI). J Voice. 2002; 16(2):274-7. DOI: 10.1016/s0892-1997(02)00097-8. View