Prolonged Outbreak of New Delhi Metallo-beta-lactamase-producing Carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019

Overview

Journal Euro Surveill

Specialty Infectious Diseases

Date 2020 Feb 20

PMID 32070467

Citations 35

Authors

Lara Tavoschi

Silvia Forni

Andrea Porretta

Lorenzo Righi

Filippo Pieralli

Francesco Menichetti

Marco Falcone

Giulia Gemignani

Spartaco Sani

Paola Vivani

Tommaso Bellandi

Danilo Tacconi

Lucia Turini

Giulio Toccafondi

Gaetano Privitera

Pierluigi Lopalco

Angelo Baggiani

Fabrizio Gemmi

Grazia Luchini

Maurizio Petrillo

Lorenzo Roti

Patrizio Pezzotti

Annalisa Pantosti

Stefania Iannazzo

Maria Teresa Mechi

Gian Maria Rossolini

Affiliations

Soon will be listed here.

Abstract

In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.

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