Treatment of Osteoarthritis Secondary to Developmental Dysplasia of the Hip with Prolotherapy Injection Versus a Supervised Progressive Exercise Control

Overview

Journal Med Sci Monit

Specialties General Medicine
Pathology

Date 2020 Feb 12

PMID 32045406

Citations 3

Authors

Deniz Gul

Aydan Orscelik

Serkan Akpancar

Affiliations

Soon will be listed here.

Abstract

BACKGROUND Osteoarthritis secondary to developmental dysplasia of the hip (DDH) is one of the major causes of hip pain and disability. The aim of the study was to compare the effectiveness of prolotherapy (PrT) injections versus exercise protocol for the treatment of DDH. MATERIAL AND METHODS There were 46 hips of 41 patients who had osteoarthritis secondary to DDH included in this study. Patients were divided into 2 groups: treated with PrT (PrT group; n=20) and exercise (control group; n=21). Clinical outcomes were evaluated with visual analog scale for pain (VAS) and Harris hip score (HHS) at baseline, 3 weeks, 3 months, 6 months, and a minimum of 1-year follow-up. In PrT group clinical results were also compared in Crowe type I-IV hips. RESULTS Between group analysis revealed no significant between group differences at baseline. Dextrose injection recipients out performed exercise controls for VAS pain change score at 6 months (-4.6±2.6 versus -2.8±2.5; P=0.016), and 12 months (-4.5±2.4 versus -2.9±2.5; P=0.017) and for HHS at 6 months (24.2±14.0 versus 14.8±12.4; P=0.007) and 12 months (24.3±13.4 versus 16.5±11.3; P=0.018). CONCLUSIONS To our best knowledge, this study is the first regarding the effects of an injection method in the treatment of osteoarthritis secondary to DDH. According to our study, PrT is superior to exercises. PrT could provide significant improvement for clinical outcomes in DDH and might delay surgery.

Citing Articles

Neglected Developmental Hip Dysplasia Treated With External Iliofemoral Distraction, Open Reduction, and Pelvic Osteotomy: Eleven-Year Follow-Up.

Amin O, AlAmoudi S, Amin B, Alamoudi A J Am Acad Orthop Surg Glob Res Rev. 2024; 8(6).

PMID: 38834537 PMC: 11152860. DOI: 10.5435/JAAOSGlobal-D-23-00291.

Efficacy of Prolotherapy for Osteoarthritis: A Systematic Review.

Waluyo Y, Artika S, Insani Nanda Wahyuni , Khaliq Gunawan A, Fadillah Zainal A J Rehabil Med. 2023; 55:jrm00372.

PMID: 36847731 PMC: 9989868. DOI: 10.2340/jrm.v55.2572.

Effectiveness of Perineural Injections Combined with Standard Postoperative Total Knee Arthroplasty Protocols in the Management of Chronic Postsurgical Pain After Total Knee Arthroplasty.

Guzel I, Gul D, Akpancar S, Lyftogt J Med Sci Monit. 2021; 27:e928759.

PMID: 33547269 PMC: 7874529. DOI: 10.12659/MSM.928759.

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