Hypothalamic Lipoma and Growth Hormone Deficiency

Overview

Journal Int J Pediatr Endocrinol

Publisher Biomed Central

Specialty Pediatrics

Date 2020 Feb 12

PMID 32042280

Citations 2

Authors

Anne Rochtus

Joseph Vinckx

Francis de Zegher

Affiliations

Soon will be listed here.

Abstract

Background: Intracranial lipomas are rare, congenital lesions, most often located at the midline. Most hypothalamic lipomas are asymptomatic, but some cases have been associated with precocious puberty, hypothermia, headache and/or obesity.

Case Presentation: A 7-year-old boy was referred for short stature and proved to be partially growth-hormone deficient. Magnetic resonance imaging (MRI) revealed a lipoma in the paramedian hypothalamus. Growth hormone treatment resulted in swift and uncomplicated catch-up growth.

Conclusions: The present case appears to be the first to link hypothalamic lipoma to GH deficiency. The neuro-endocrine pathophysiology underpinning this link remains to be explored.

Citing Articles

Intracranial Lipoma Extending Extracranially in a Five-Year-Old Patient.

Elgassim M, Wafer A, Ahmed A, Elfaki A, Satti A, Anjum S Cureus. 2022; 14(2):e21816.

PMID: 35261835 PMC: 8894121. DOI: 10.7759/cureus.21816.

Corpus callosal lipoma in a young adult with extracranial extension, presenting as a frontal scalp swelling: A rare case report.

Esmat H Radiol Case Rep. 2021; 16(3):534-537.

PMID: 33384751 PMC: 7770449. DOI: 10.1016/j.radcr.2020.12.040.

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