The Utility of Bronchoscopy in Immunocompromised Patients: a Review
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Bronchoscopy is an important tool for the diagnosis of pulmonary disorders in immunocompromised patients. The addition of biopsies to bronchoalveolar lavage improves the diagnostic yield of non-infectious etiologies, although the underlying etiology of the immunocompromised state must be considered and may be influential. Certain unknowns remain, including timing of bronchoscopy and its impact on medical management and mortality. The ongoing role of non-invasive testing for infectious complications prior to bronchoscopy also remains to be defined. This review addresses the role of bronchoscopy in immunocompromised states related to underlying hematologic malignancies, prescription drug use or chemotherapy, and other disorders that predispose patients to infectious or non-infectious pulmonary diseases.
Oliveira J, Cano C, Junior J, Barreto G, Mendes F, de Melo R Hematol Transfus Cell Ther. 2025; 47(1):103741.
PMID: 39978056 PMC: 11880693. DOI: 10.1016/j.htct.2025.103741.
A Longitudinal Study of Multimodal Bronchoscopy Training in Uganda.
Karmali D, Argento A, Kirenga B, Batra H, Lee H, MacRosty C ATS Sch. 2023; 4(2):152-163.
PMID: 37538081 PMC: 10394594. DOI: 10.34197/ats-scholar.2022-0080OC.
Nakamura T, Imai R, Kitamura A, So C, Ro S, Okafuji K Cureus. 2023; 15(5):e38820.
PMID: 37303378 PMC: 10256251. DOI: 10.7759/cureus.38820.
Performance of a new single-use bronchoscope versus a marketed single-use comparator: a bench study.
Lamb C, Yavarovich E, Kang V, Servais E, Sheehan L, Shadchehr S BMC Pulm Med. 2022; 22(1):189.
PMID: 35550062 PMC: 9095814. DOI: 10.1186/s12890-022-01982-4.
Ing M, Williamson J Breathe (Sheff). 2021; 16(4):200210.
PMID: 33447292 PMC: 7792854. DOI: 10.1183/20734735.0210-2020.