» Articles » PMID: 32021673

Muscle Recovery Is Highlighted by IR Laser Therapy

Overview
Date 2020 Feb 6
PMID 32021673
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

In sports medicine, laser application has been well-established for the recovery of muscles. The mechanisms by which benefits of this kind of therapy can be studied is molecular research approach. Protein-protein interaction network analysis as one of the important complementary studies of proteomics can accelerate this goal by the identification of novel contributing markers. By the use of Cytoscape V3.7.1 and its applications, a network of differential expressed proteins (DEPs) from IR laser treatment samples were constructed and analyzed. Six hub-bottlenecks were determined, 4 of which were from differentially expressed proteins. ClueGO discovered 4 biological processes related to these hub-bottlenecks that their function could alter due to IR laser therapy. In fact, by the expression changes of hub-bottlenecks including the up-regulation of HSP90s, one of the prominent biological processes in muscle recovery could be activated. This process is called nitric oxide synthase (NOS) activation that could be proposed as one of the underlying mechanisms of IR laser treatments in muscle recovery.

Citing Articles

Introducing Critical Genes in Response to Photodynamic Therapy: A Network Analysis.

Mansouri V, Arjmand B, Hamzeloo-Moghadam M, Rezaei Tavirani M, Razzaghi Z, Ahmadzadeh A J Lasers Med Sci. 2023; 14:e25.

PMID: 37744009 PMC: 10517577. DOI: 10.34172/jlms.2023.25.


Neuroprotective Properties of Photobiomodulation in Retinal Regeneration in Rats: Perspectives From Interaction Levels.

Mansouri V, Razzaghi M, Rostami-Nejad M, Rezaei-Tavirani M, Heidari M, Safari S J Lasers Med Sci. 2020; 11(3):280-286.

PMID: 32802288 PMC: 7369552. DOI: 10.34172/jlms.2020.47.


Immunological reactions by T cell and regulation of crucial genes in treated celiac disease patients.

Rostami-Nejad M, Razzaghi Z, Esmaeili S, Rezaei-Tavirani S, Baghban A, Vafaee R Gastroenterol Hepatol Bed Bench. 2020; 13(2):155-160.

PMID: 32308937 PMC: 7149810.


Assessment of Dysregulation of HERC6 and Essential Biological Processes in Response to Laser Therapy of Human Arm Skin.

Safari S, Rostami-Nejad M, Rezaei-Tavirani M, Mansouri V, Razzaghi Z, Rezaei-Tavirani M J Lasers Med Sci. 2020; 11(2):115-119.

PMID: 32273950 PMC: 7118510. DOI: 10.34172/jlms.2020.20.

References
1.
Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A . ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics. 2009; 25(8):1091-3. PMC: 2666812. DOI: 10.1093/bioinformatics/btp101. View

2.
Pilegaard H, Ordway G, Saltin B, Neufer P . Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab. 2000; 279(4):E806-14. DOI: 10.1152/ajpendo.2000.279.4.E806. View

3.
Bindea G, Galon J, Mlecnik B . CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data. Bioinformatics. 2013; 29(5):661-3. PMC: 3582273. DOI: 10.1093/bioinformatics/btt019. View

4.
Rezaie-Tavirani M, Hasanzadeh H, Seyyedi S, Zali H . Proteomic Analysis of the Effect of Extremely Low-Frequency Electromagnetic Fields (ELF-EMF) With Different Intensities in SH-SY5Y Neuroblastoma Cell Line. J Lasers Med Sci. 2017; 8(2):79-83. PMC: 5474386. DOI: 10.15171/jlms.2017.14. View

5.
Anderson J . A role for nitric oxide in muscle repair: nitric oxide-mediated activation of muscle satellite cells. Mol Biol Cell. 2000; 11(5):1859-74. PMC: 14889. DOI: 10.1091/mbc.11.5.1859. View