Metabolic Effect of the Hepatic Branch of the Vagal Nerve in One-Anastomosis Gastric Bypass (OAGB)

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2020 Feb 6

PMID 32020329

Citations 5

Authors

Jaime Ruiz-Tovar

Carolina Llavero

Affiliations

Soon will be listed here.

Abstract

Background: Bariatric surgery is often performed not only to lose weight, but also to improve obesity-related comorbidities. A certain metabolic effect of the bariatric techniques has been demonstrated, as the improvement or even remission of comorbidities is patent, before having lost a relevant amount of weight. The autonomic innervation of diverse viscera by the vagus nerve has been hypothesized to participate in it. We aimed to evaluate the ponderal and metabolic impact of the preservation of the hepatic branch of the vagus in type 2 diabetic (T2D) patients undergoing one-anastomosis gastric bypass (OAGB).

Patients And Methods: We conducted a prospective study on patients with a preoperative diagnosis of morbid obesity and T2D, who underwent an OAGB. Preservation of the hepatic branch of the vagus was carried out in the first 14 patients (Group 1), whereas in another 14 patients it was sectioned. Ponderal and metabolic outcomes were assessed 1 and 2 years after surgery.

Results: The length of the biliary limb was 210 cm in both groups. Postoperative BMI or excess BMI loss was not significantly different between groups. The patients included in Group 1 showed a statistically greater improvement in glycemic and lipid variables.

Conclusion: The preservation of the hepatic branch of the vagus in an OAGB leads to more favorable postoperative glycemic and lipid profiles.

Citing Articles

Technical Variations and Considerations around OAGB in IFSO-APC and IFSO-MENAC Chapters, an Expert Survey.

Kermansaravi M, Shahmiri S, Kow L, Gawdat K, Abbas S, Aly A Obes Surg. 2024; 34(6):2054-2065.

PMID: 38662251 DOI: 10.1007/s11695-024-07239-9.

GLP-1 Increases Circulating Leptin Levels in Truncal Vagotomized Rats.

Morais T, Pereira S, Andrade S, Neves D, Guimaraes M, Nora M Biomedicines. 2023; 11(5).

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Effect of Biliopancreatic Limb Length on Weight Loss, Postoperative Complications, and Remission of Comorbidities in One Anastomosis Gastric Bypass: a Systematic Review and Meta-analysis.

Tasdighi E, Barzin M, Mahawar K, Hosseinpanah F, Ebadinejad A, Taraghikhah N Obes Surg. 2022; 32(3):892-903.

PMID: 35091899 DOI: 10.1007/s11695-021-05848-2.

Impact of the Hepatic Branch of the Vagus Nerve Transection in Laparoscopic Sleeve Gastrectomy for Patients with Obesity and Type 2 Diabetes Mellitus.

Sano A, Seki Y, Kasama K, Nabekura T, Kurokawa Y, Ubukata Y Obes Surg. 2021; 31(9):3926-3935.

PMID: 34081275 DOI: 10.1007/s11695-021-05510-x.

Areas of Non-Consensus Around One Anastomosis/Mini Gastric Bypass (OAGB/MGB): A Narrative Review.

Kermansaravi M, DavarpanahJazi A, ShahabiShahmiri S, Carbajo M, Vitiello A, Parmar C Obes Surg. 2021; 31(6):2453-2463.

PMID: 33598845 DOI: 10.1007/s11695-021-05276-2.

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