Possible Drug-induced, Vision-threatening Maculopathy Secondary to Chronic Pentosan Polysulfate Sodium (Elmiron) Exposure

Overview

Journal Can Urol Assoc J

Specialty Urology

Date 2020 Jan 31

PMID 31999543

Citations 4

Authors

R Christopher Doiron

Mark Bona

J Curtis Nickel

Affiliations

Soon will be listed here.

Citing Articles

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study.

Hswen Y, Qin Q, Smith P, Swierczynski A, Bauer S, Ladson E JMIR Form Res. 2025; 9:e54209.

PMID: 39864816 PMC: 11769693. DOI: 10.2196/54209.

Systemic Medications and Their Ocular Side Effects.

Al-Namaeh M Cureus. 2025; 16(12):e74976.

PMID: 39744265 PMC: 11692015. DOI: 10.7759/cureus.74976.

Real-World Practices of Pentosan Polysulfate Maculopathy Screening in Various Clinical Settings and Practice-Associated Factors.

Kim J, Ahn S J Clin Med. 2024; 13(17).

PMID: 39274302 PMC: 11396709. DOI: 10.3390/jcm13175090.

Rosenberg D, Sarraf D, Chaudhary V CMAJ. 2021; 193(29):E1147-E1148.

PMID: 34312174 PMC: 8321295. DOI: 10.1503/cmaj.201900-f.

Maculopathy caused by pentosan polysulfate.

Rosenberg D, Sarraf D, Chaudhary V CMAJ. 2021; 193(18):E645.

PMID: 33941523 PMC: 8112634. DOI: 10.1503/cmaj.201900.

References

Jain N, Li A, Yu Y, VanderBeek B . Association of macular disease with long-term use of pentosan polysulfate sodium: findings from a US cohort. Br J Ophthalmol. 2019; 104(8):1093-1097. PMC: 7288845. DOI: 10.1136/bjophthalmol-2019-314765. View

Nickel J, Moldwin R . FDA BRUDAC 2018 Criteria for Interstitial Cystitis/Bladder Pain Syndrome Clinical Trials: Future Direction for Research. J Urol. 2018; 200(1):39-42. DOI: 10.1016/j.juro.2018.02.011. View

Pearce W, Chen R, Jain N . Pigmentary Maculopathy Associated with Chronic Exposure to Pentosan Polysulfate Sodium. Ophthalmology. 2018; 125(11):1793-1802. DOI: 10.1016/j.ophtha.2018.04.026. View

Nickel J, Herschorn S, Whitmore K, Forrest J, Hu P, Friedman A . Pentosan polysulfate sodium for treatment of interstitial cystitis/bladder pain syndrome: insights from a randomized, double-blind, placebo controlled study. J Urol. 2014; 193(3):857-62. DOI: 10.1016/j.juro.2014.09.036. View

Hanif A, Armenti S, Taylor S, Shah R, Igelman A, Jayasundera K . Phenotypic Spectrum of Pentosan Polysulfate Sodium-Associated Maculopathy: A Multicenter Study. JAMA Ophthalmol. 2019; 137(11):1275-1282. PMC: 6735406. DOI: 10.1001/jamaophthalmol.2019.3392. View