In Vitro Characterization of Virulence Factors Among Species of the Candida Parapsilosis Complex

Overview

Journal Rev Soc Bras Med Trop

Specialty Tropical Medicine

Date 2020 Jan 30

PMID 31994664

Citations 1

Authors

Fabio Silvestre Ataides

Carolina Rodrigues Costa

Andressa Santana Santos

Vivianny Aparecida Queiroz Freitas

Thaisa Cristina Silva

Ana Laura Sene Amancio Zara

Rosalia Santos Amorim Jesuino

Maria Rosario Rodrigues Silva

Affiliations

Soon will be listed here.

Abstract

Introduction: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence.

Methods: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains.

Results: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells.

Conclusions: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells.

Citing Articles

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PMID: 37681981 PMC: 10583669. DOI: 10.1128/aac.00534-23.

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