One-Step Multichannel Percutaneous Transhepatic Cholangioscopic Lithotripsy Applied in Bilateral Hepatolithiasis
Overview
Authors
Affiliations
Background: The aim of this study was to compare the outcomes of one-step multichannel percutaneous transhepatic cholangioscopic lithotripsy (PTCSL) with traditional PTCSL in the treatment of bilateral hepatolithiasis.
Methods: From February 2011 to June 2015, 156 patients with bilateral hepatolithiasis received surgical treatment in our department. Among these patients, 81 received one-step multichannel PTCSL (group A), and the remaining 75 received traditional PTCSL (group B).
Results: Compared with group B, group A was characterized by a significantly shorter operation time (83.7 ± 28.5 min vs 118.1 ± 41.5 min; P = 0.000), hospital stay (11.1 ± 3.4 d vs 17.8 ± 5.6 d; P = 0.034), and postoperative hospital stay (6.9 ± 3.1 d vs 9.6 ± 4.5 d; P = 0.026). In addition, the immediate clearance (62.9% vs 45.3%, P = 0.027) and final clearance (90.1% vs 78.7%, P = 0.048) rates were higher in group A than in group B. During the follow-up period, stone recurrence was significantly less common in group A than in group B (13.6% vs 26.7%, P = 0.041). Multivariate Cox analysis showed that the PTCSL method (HR = 2.32, 95% confidence interval [CI] = 1.09-4.90, P = 0.028), bilateral biliary stricture (HR = 4.17, 95% CI = 1.73-10.03, P = 0.001), and stones located in segments I (HR = 7.75, 95% CI = 3.67-16.38, P = 0.000) were independent predictors of recurrence.
Conclusions: Compared with traditional PTCSL, one-step multichannel PTCSL was more efficient and effective in the treatment of bilateral hepatolithiasis.
Chen P, Bai M, Cai R, Chen M, Zhu Z, Wu F Updates Surg. 2025; .
PMID: 39930257 DOI: 10.1007/s13304-025-02118-z.
Zhou Y, Xie Y, Cai N, Liang Y, Gong R, Wang P Med Biol Eng Comput. 2024; 63(1):127-138.
PMID: 39177918 DOI: 10.1007/s11517-024-03183-z.
Percutaneous transhepatic choledochoscopy in the management of hepatolithiasis: a narrative review.
Wang S, Wu S Quant Imaging Med Surg. 2024; 14(7):5164-5175.
PMID: 39022230 PMC: 11250287. DOI: 10.21037/qims-24-421.
Cheng L, Niu J, Cheng Y, Liu J, Shi M, Huang S J Inflamm Res. 2024; 17:2575-2587.
PMID: 38686361 PMC: 11057514. DOI: 10.2147/JIR.S453653.
Hepatolithiasis: Epidemiology, presentation, classification and management of a complex disease.
Motta R, Saffioti F, Mavroeidis V World J Gastroenterol. 2024; 30(13):1836-1850.
PMID: 38659478 PMC: 11036492. DOI: 10.3748/wjg.v30.i13.1836.