Gadolinium Retention - 5 years Later…

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2020 Jan 25

PMID 31975183

Citations 3

Authors

Jonathan R Dillman

Matthew S Davenport

Affiliations

Soon will be listed here.

Citing Articles

Artificial intelligence in oncologic imaging.

Chen M, Terzic A, Becker A, Johnson J, Wu C, Wintermark M Eur J Radiol Open. 2022; 9:100441.

PMID: 36193451 PMC: 9525817. DOI: 10.1016/j.ejro.2022.100441.

Deep learning of MRI contrast enhancement for mapping cerebral blood volume from single-modal non-contrast scans of aging and Alzheimer's disease brains.

Liu C, Zhu N, Sun H, Zhang J, Feng X, Gjerswold-Selleck S Front Aging Neurosci. 2022; 14:923673.

PMID: 36034139 PMC: 9407020. DOI: 10.3389/fnagi.2022.923673.

Gadolinium retention: should pediatric radiologists be concerned, and how to frame conversations with families.

Noda S, Oztek M, Stanescu A, Maloney E, Shaw D, Iyer R Pediatr Radiol. 2021; 52(2):345-353.

PMID: 33978802 DOI: 10.1007/s00247-021-04973-5.

References

Sieber M, Lengsfeld P, Frenzel T, Golfier S, Schmitt-Willich H, Siegmund F . Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions. Eur Radiol. 2008; 18(10):2164-73. DOI: 10.1007/s00330-008-0977-y. View

Kanda T, Ishii K, Kawaguchi H, Kitajima K, Takenaka D . High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology. 2014; 270(3):834-41. DOI: 10.1148/radiol.13131669. View

Grobner T . Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?. Nephrol Dial Transplant. 2006; 21(4):1104-8. DOI: 10.1093/ndt/gfk062. View

McDonald R, Levine D, Weinreb J, Kanal E, Davenport M, Ellis J . Gadolinium Retention: A Research Roadmap from the 2018 NIH/ACR/RSNA Workshop on Gadolinium Chelates. Radiology. 2018; 289(2):517-534. PMC: 6209069. DOI: 10.1148/radiol.2018181151. View

Ryu Y, Choi Y, Cheon J, Lee W, Park S, Park J . Pediatric Brain: Gadolinium Deposition in Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted Images Is Dependent on the Type of Contrast Agent. Invest Radiol. 2018; 53(4):246-255. DOI: 10.1097/RLI.0000000000000436. View

McDonald R, McDonald J, Bida J, Carter R, Fleming C, Misra S . Intravenous contrast material-induced nephropathy: causal or coincident phenomenon?. Radiology. 2013; 267(1):106-18. PMC: 6940002. DOI: 10.1148/radiol.12121823. View

Kanda T, Fukusato T, Matsuda M, Toyoda K, Oba H, Kotoku J . Gadolinium-based Contrast Agent Accumulates in the Brain Even in Subjects without Severe Renal Dysfunction: Evaluation of Autopsy Brain Specimens with Inductively Coupled Plasma Mass Spectroscopy. Radiology. 2015; 276(1):228-32. DOI: 10.1148/radiol.2015142690. View

Hu H, Pokorney A, Towbin R, Miller J . Increased signal intensities in the dentate nucleus and globus pallidus on unenhanced T1-weighted images: evidence in children undergoing multiple gadolinium MRI exams. Pediatr Radiol. 2016; 46(11):1590-8. DOI: 10.1007/s00247-016-3646-3. View

Errante Y, Cirimele V, Mallio C, Di Lazzaro V, Zobel B, Cosimo Quattrocchi C . Progressive increase of T1 signal intensity of the dentate nucleus on unenhanced magnetic resonance images is associated with cumulative doses of intravenously administered gadodiamide in patients with normal renal function, suggesting dechelation. Invest Radiol. 2014; 49(10):685-90. DOI: 10.1097/RLI.0000000000000072. View

10.

Davenport M, Khalatbari S, Cohan R, Dillman J, Myles J, Ellis J . Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material: risk stratification by using estimated glomerular filtration rate. Radiology. 2013; 268(3):719-28. DOI: 10.1148/radiol.13122276. View

11.

Franano F, Edwards W, Welch M, Brechbiel M, Gansow O, Duncan J . Biodistribution and metabolism of targeted and nontargeted protein-chelate-gadolinium complexes: evidence for gadolinium dissociation in vitro and in vivo. Magn Reson Imaging. 1995; 13(2):201-14. DOI: 10.1016/0730-725x(94)00100-h. View

12.

Marckmann P, Skov L, Rossen K, Dupont A, Damholt M, Heaf J . Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging. J Am Soc Nephrol. 2006; 17(9):2359-62. DOI: 10.1681/ASN.2006060601. View

13.

Ray D, CAVANAGH J, Nolan C, Williams S . Neurotoxic effects of gadopentetate dimeglumine: behavioral disturbance and morphology after intracerebroventricular injection in rats. AJNR Am J Neuroradiol. 1996; 17(2):365-73. PMC: 8338359. View

14.

McDonald J, McDonald R, Jentoft M, Paolini M, Murray D, Kallmes D . Intracranial Gadolinium Deposition Following Gadodiamide-Enhanced Magnetic Resonance Imaging in Pediatric Patients: A Case-Control Study. JAMA Pediatr. 2017; 171(7):705-707. PMC: 6583486. DOI: 10.1001/jamapediatrics.2017.0264. View

15.

Kasper E, Schemuth H, Horry S, Kinner S . Changes in signal intensity in the dentate nucleus at unenhanced T1-weighted magnetic resonance imaging depending on class of previously used gadolinium-based contrast agent. Pediatr Radiol. 2018; 48(5):686-693. DOI: 10.1007/s00247-018-4080-5. View

16.

Roberts D, Chatterjee A, Yazdani M, Marebwa B, Brown T, Collins H . Pediatric Patients Demonstrate Progressive T1-Weighted Hyperintensity in the Dentate Nucleus following Multiple Doses of Gadolinium-Based Contrast Agent. AJNR Am J Neuroradiol. 2016; 37(12):2340-2347. PMC: 5161565. DOI: 10.3174/ajnr.A4891. View

17.

Rossi Espagnet M, Bernardi B, Pasquini L, Figa-Talamanca L, Toma P, Napolitano A . Signal intensity at unenhanced T1-weighted magnetic resonance in the globus pallidus and dentate nucleus after serial administrations of a macrocyclic gadolinium-based contrast agent in children. Pediatr Radiol. 2017; 47(10):1345-1352. DOI: 10.1007/s00247-017-3874-1. View

18.

McDonald R, McDonald J, Kallmes D, Jentoft M, Paolini M, Murray D . Gadolinium Deposition in Human Brain Tissues after Contrast-enhanced MR Imaging in Adult Patients without Intracranial Abnormalities. Radiology. 2017; 285(2):546-554. DOI: 10.1148/radiol.2017161595. View

19.

. The ALARA (as low as reasonably achievable) concept in pediatric CT intelligent dose reduction. Multidisciplinary conference organized by the Society of Pediatric Radiology. August 18-19, 2001. Pediatr Radiol. 2002; 32(4):217-313. DOI: 10.1007/s00247-002-0665-z. View