Whole-body Diffusion-weighted Imaging with Background Body Signal Suppression in the Detection of Osseous and Extra-osseous Metastases

Overview

Journal Pol J Radiol

Publisher Termedia

Specialty Radiology

Date 2020 Jan 24

PMID 31969965

Citations 6

Authors

Ahmed Abdel Razek

Ahmed Tawfik

Mariam Abdel Rahman

Saleh Teima

Affiliations

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Abstract

Purpose: To assess the reproducibility of detection of osseous and extra-osseous metastases in cancer patients using whole-body diffusion-weighted imaging with background body signal suppression (WB-DWIBS).

Material And Methods: A prospective study was conducted on 39 consecutive patients (21 females, 18 males; mean age 48 years) with metastases, who underwent WB-DWIBS on a 1.5-T MR scanner. Image analysis was performed independently by two blinded observers. Inter-observer agreement was assessed for the detection of osseous (spinal, appendicular) and extra-osseous (hepatic, pulmonary, nodal, and peritoneal) metastases.

Results: The overall inter-observer agreement of WB-DWIBS in the detection of osseous and extra-osseous metastases was excellent (κ = 0.887, agreement = 94.44%, = 0.001). There was excellent inter-observer agreement of both observers for the detection of osseous spinal (κ = 0.846, agreement = 92.3%), osseous appendicular (κ = 0.898, agreement = 94.8 %), hepatic (κ = 0.847, agreement = 92.3%), pulmonary (κ = 0.938, agreement = 97.4%), nodal metastases (κ = 0.856, agreement = 94.9%), and peritoneal metastasis (κ = 0.772, agreement = 94.9%).

Conclusion: We concluded that WB-DWIBS is reproducible for detection of osseous and extra-osseous metastases in cancer patients.

Citing Articles

Whole-body diffusion-weighted imaging with background body signal suppression and quantitative apparent diffusion coefficient in the detection, staging, and grading of non-Hodgkin lymphoma.

Razek A, Tawfik A, Rahman M, Teima S, Batouty N Pol J Radiol. 2023; 88:e177-e186.

PMID: 37057202 PMC: 10086610. DOI: 10.5114/pjr.2023.126393.

Stereotactic Body Radiotherapy for a Sacral Metastasis Clarified by Diffusion-Weighted Whole-Body Imaging With Background Body Signal Suppression in a Patient With Castration-Resistant Prostate Cancer.

Katano A, Takeuchi K, Yamashita H, Nakagawa K Cureus. 2022; 14(3):e23047.

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Zhang B, Bian B, Zhao Z, Lin F, Zhu Z, Lou M BMC Med Imaging. 2021; 21(1):98.

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Zhong X, Jiang H, Mai H, Xiang J, Li J, Huang Z Cancer Imaging. 2020; 20(1):76.

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