» Articles » PMID: 31967091

Multicenter Screening of Diabetic Patients for Detecting New Cases of Tuberculosis: an Approach to Intensify the Case Detection Rate of Tuberculosis in Developing Countries with High Prevalence of Diabetes

Overview
Journal J Prev Med Hyg
Specialty Public Health
Date 2020 Jan 23
PMID 31967091
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Introduction: Tuberculosis (TB) is a major public health problem in most of developing countries. Meanwhile, the prevalence of type 2 diabetes mellitus (DM) is also increasing rapidly.

Objectives: To describe the feasibility of implementing screening test for tuberculosis among diabetic patients and identifying factors associated with high detection rate.

Methods: Study Design: Multi-center cross-sectional study. This study was implemented in the governmental healthcare settings. To diagnose TB among diabetics, we used a symptom-based questionnaire that included the symptoms of suspected TB according to the guidelines of National Tuberculosis Program in Egypt.

Results: Among 4283 adult diabetics, 14 TB cases were diagnosed; 9 known TB cases and 5 newly detected cases. The number needed to detect one new case of TB was 855. Male diabetics and who those suffered from liver disease experienced a significantly higher prevalence of TB and a higher detection rate of new active cases.

Conclusions: Screening for TB among diabetics in routine governmental healthcare services was successfully implemented. Screening DM patients in countries with a high prevalence of DM will reveal a significant number of active TB cases, which will in turn improve the case detection rate of TB.

Citing Articles

Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry.

Mohan R, Rajalakshmi M, Kalaiselvan G J Family Med Prim Care. 2025; 14(1):290-295.

PMID: 39989519 PMC: 11844953. DOI: 10.4103/jfmpc.jfmpc_1108_24.


The yield of chest X-ray based versus symptom-based screening among patients with diabetes mellitus in public health facilities in Addis Ababa, Ethiopia.

Jerene D, Muleta C, Dressie S, Ahmed A, Tarekegn G, Haile T J Clin Tuberc Other Mycobact Dis. 2022; 29:100333.

PMID: 36238947 PMC: 9551073. DOI: 10.1016/j.jctube.2022.100333.


Incidence and prevalence of pulmonary tuberculosis among patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

Wu Q, Liu Y, Ma Y, Liu K, Chen S Ann Med. 2022; 54(1):1657-1666.

PMID: 35703920 PMC: 9225779. DOI: 10.1080/07853890.2022.2085318.

References
1.
Castellanos-Joya M, Delgado-Sanchez G, Ferreyra-Reyes L, Cruz-Hervert P, Ferreira-Guerrero E, Ortiz-Solis G . Results of the implementation of a pilot model for the bidirectional screening and joint management of patients with pulmonary tuberculosis and diabetes mellitus in Mexico. PLoS One. 2014; 9(9):e106961. PMC: 4167852. DOI: 10.1371/journal.pone.0106961. View

2.
Lin Y, Chen C, Chen P, Huang J, Ho C, Weng H . Screening for pulmonary tuberculosis in type 2 diabetes elderly: a cross-sectional study in a community hospital. BMC Public Health. 2015; 15:3. PMC: 4324855. DOI: 10.1186/1471-2458-15-3. View

3.
Harries A, Satyanarayana S, Kumar A, Nagaraja S, Isaakidis P, Malhotra S . Epidemiology and interaction of diabetes mellitus and tuberculosis and challenges for care: a review. Public Health Action. 2015; 3(Suppl 1):S3-9. PMC: 4463136. DOI: 10.5588/pha.13.0024. View

4.
Ohene S, Bonsu F, Hanson-Nortey N, Toonstra A, Sackey A, Lonnroth K . Provider initiated tuberculosis case finding in outpatient departments of health care facilities in Ghana: yield by screening strategy and target group. BMC Infect Dis. 2017; 17(1):739. PMC: 5709967. DOI: 10.1186/s12879-017-2843-5. View

5.
Feleke Y, Abdulkadir J, Aderaye G . Prevalence and clinical features of tuberculosis in Ethiopian diabetic patients. East Afr Med J. 1999; 76(7):361-4. View