Comparative Genomic Analysis of : An Insight into Genomic Diversity and Genome Evolution

, a member of the genus, is a gram-positive pathogenic bacterium. possesses an open pan-genome that constitutes the basis of its high genomic diversity and allows for adaptation to specific niche conditions and the changing host environments. Our analysis further showed that the core genome of contributes to the pathogenicity and niche adaptation of . Comparative genomic analysis revealed that the genomes of shared identical collinearity relationship, and heterogeneity was mainly acquired by means of genomic islands and prophages. Moreover, genomic islands in were always involved in virulence, resistance, or niche adaptation and possibly working with prophages to cause the majority of genome expansion. These findings provide an insight into the genomic diversity, evolution, and structural variation of and a valuable resource for functional genomic studies.