Adrenal Cavernous Hemangioma: A Rarely Perceived Pathology-Case Illustration and Review of Literature

Overview

Journal Case Rep Pathol

Publisher Wiley

Specialty Pathology

Date 2020 Jan 18

PMID 31949968

Citations 10

Authors

Jad A Degheili

Nassib F Abou Heidar

Mouhammad El-Moussawi

Ayman Tawil

Rami W Nasr

Affiliations

Soon will be listed here.

Abstract

Cavernous hemangiomas are endothelial tumors that rarely affect the adrenal glands. Most of these tumors remain silent and are incidentally found on abdominal imaging. Hardly ever, these tumors are endocrinologically functional. They may present as vague abdominal pain. Surgical resection remains the mainstay for large masses. In this paper, we are presenting a case of adrenal cavernous hemangioma in a 83-year-old male patient who initially presented for workup of vague abdominal and bilateral flank pain. A computed tomography scan of the abdomen showed an 8 cm right adrenal adenoma which was metabolically nonfunctional. The mass was completely resected through an open subcostal incision, with no encountered postoperative complications. A highlight of all published cases of adrenal hemangiomas since 1955 is also presented and reviewed.

Citing Articles

The diagnostic dilemma of adrenal vascular tumors: analysis of 21 cases and systematic review of the literature.

Coscia K, Ravaioli C, Tucci L, Colombin G, Donnarumma F, Mosconi C Endocrine. 2025; 87(3):1291-1304.

PMID: 39825193 PMC: 11845438. DOI: 10.1007/s12020-024-04123-5.

A case of adrenal cavernous hemangioma resected due to tumor growth accompanied by intratumoral hemorrhage.

Ueda T, Yanagi M, Kusakabe T, Shigihara T, Shibasaki M, Nagasawa M IJU Case Rep. 2024; 7(5):379-382.

PMID: 39224674 PMC: 11366426. DOI: 10.1002/iju5.12760.

Rare adrenal cavernous hemangioma: a case report highlighting diagnostic challenges.

Antar R, Farag C, Youssef K, Xu V, Drouaud A, Panitch N Front Surg. 2023; 10:1293925.

PMID: 38026486 PMC: 10667707. DOI: 10.3389/fsurg.2023.1293925.

Incidental adrenal hemangioma clinically suspicious for malignancy: diagnostic considerations and review of the literature.

Toklu A, Mesa H, Collins K Int J Clin Exp Pathol. 2022; 15(11):444-458.

PMID: 36507066 PMC: 9729942.

A Rare Case of Cavernous Haemangioma of the Adrenal Gland: A Case Report and Review of Literature.

Chua Y, Quake S, Prasad K, Elsaify W Cureus. 2022; 14(10):e29917.

PMID: 36348862 PMC: 9633059. DOI: 10.7759/cureus.29917.

References

Quint L, Glazer G, Francis I, Shapiro B, Chenevert T . Pheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintigraphy. Radiology. 1987; 165(1):89-93. DOI: 10.1148/radiology.165.1.3628794. View

Matsuda D, Iwamura M, Baba S . Cavernous hemangioma of the adrenal gland. Int J Urol. 2009; 16(4):424. DOI: 10.1111/j.1442-2042.2009.02260.x. View

Aljabri K, Bokhari S, Alkeraithi M . Adrenal hemangioma in a 19-year-old female. Ann Saudi Med. 2011; 31(4):421-3. PMC: 3156522. DOI: 10.4103/0256-4947.76411. View

Elfenbein D, Scarborough J, Speicher P, Scheri R . Comparison of laparoscopic versus open adrenalectomy: results from American College of Surgeons-National Surgery Quality Improvement Project. J Surg Res. 2013; 184(1):216-20. DOI: 10.1016/j.jss.2013.04.014. View

Bhat H, Tiyadath B . Management of Adrenal Masses. Indian J Surg Oncol. 2017; 8(1):67-73. PMC: 5236029. DOI: 10.1007/s13193-016-0597-y. View

Marotti M, Sucic Z, Krolo I, Dimanovski J, Klaric R, Ferencic Z . Adrenal cavernous hemangioma: MRI, CT, and US appearance. Eur Radiol. 1997; 7(5):691-4. DOI: 10.1007/BF02742927. View

Thiele J, Bodie B . Adrenal hemangioma. Surgery. 2001; 129(3):373-4. DOI: 10.1067/msy.2001.105653. View

Lee W, WEINREB J, Kumari S, Phillips G, Pochaczevsky R, Pillari G . Case report. Adrenal hemangioma. J Comput Assist Tomogr. 1982; 6(2):392-4. DOI: 10.1097/00004728-198204000-00028. View

Iwamoto G, Shimokihara K, Kawahara T, Takamoto D, Yao M, Teranishi J . Adrenal Hemangioma: A Case of Retroperitoneal Tumor. Case Rep Med. 2018; 2018:8796327. PMC: 5836307. DOI: 10.1155/2018/8796327. View

10.

Wang J, Chiang J, Chang T . Adrenal hemangioma: computed tomogram and angiogram appearances. Zhonghua Yi Xue Za Zhi (Taipei). 1992; 50(2):161-4. View

11.

Orringer R, Lynch J, McDermott W . Cavernous hemangioma of the adrenal gland. J Surg Oncol. 1983; 22(2):106-8. DOI: 10.1002/jso.2930220211. View

12.

Edwards J, Stuart H, Urbanski S, Pasieka J . A rare cavernous hemangioma of the adrenal gland. Int J Surg Case Rep. 2014; 5(2):52-5. PMC: 3921650. DOI: 10.1016/j.ijscr.2013.11.003. View

13.

Honig S, Klavans M, Hyde C, Siroky M . Adrenal hemangioma: an unusual adrenal mass delineated with magnetic resonance imaging. J Urol. 1991; 146(2):400-2. DOI: 10.1016/s0022-5347(17)37805-9. View

14.

Salup R, Finegold R, Borochovitz D, Boehnke M, Posner M . Cavernous hemangioma of the adrenal gland. J Urol. 1992; 147(1):110-2. DOI: 10.1016/s0022-5347(17)37149-5. View

15.

Peng X, Luo W, Zhang X, Zhu W . Sudden onset flank pain: a case report of retroperitoneal hemorrhage secondary to a ruptured adrenal hemangioma. J Pain Res. 2018; 11:1421-1424. PMC: 6074836. DOI: 10.2147/JPR.S160661. View

16.

Siddiqi A, Miller F, Kasuganti D, Nikolaidis P . Adrenal hemangioma-adenoma: an exceedingly rare adrenal collision tumor. J Magn Reson Imaging. 2009; 29(4):949-52. DOI: 10.1002/jmri.21430. View

17.

CHODOFF R, Smith J, Hering N . Cavernous hemangioma of the adrenal gland. Am J Surg. 1966; 111(4):595-7. DOI: 10.1016/0002-9610(66)90293-5. View

18.

Oh B, Jeong Y, Ryu S, Park Y, Kang H . A case of adrenal cavernous hemangioma. Int J Urol. 1998; 4(6):608-10. DOI: 10.1111/j.1442-2042.1997.tb00318.x. View

19.

Yamada T, Ishibashi T, Saito H, Majima K, Tsuda M, Takahashi S . Two cases of adrenal hemangioma: CT and MRI findings with pathological correlations. Radiat Med. 2002; 20(1):51-6. View

20.

Tarchouli M, Boudhas A, Ratbi M, Essarghini M, Njoumi N, Sair K . Giant adrenal hemangioma: Unusual cause of huge abdominal mass. Can Urol Assoc J. 2015; 9(11-12):E834-6. PMC: 4639440. DOI: 10.5489/cuaj.2967. View