Analysis of Multiclass Organic Pollutant in Municipal Landfill Leachate by Dispersive Liquid-liquid Microextraction and Comprehensive Two-dimensional Gas Chromatography Coupled with Mass Spectrometry

We propose a simple, fast, and inexpensive method for the analyses of 72 organic compounds in municipal landfill leachate, based on dispersive liquid-liquid microextraction and comprehensive two-dimensional gas chromatography coupled with mass spectrometry. Forty-one organic compounds belonging to several classes including hydrocarbons, mono- and polyaromatic hydrocarbons, carbonyl compounds, terpenes, terpenoids, phenols, amines, and phthalates, covering a wide range of physicochemical properties and linked to municipal landfill leachate, were quantitatively determined. Another 31 organic compounds such as indoles, pyrroles, glycols, organophosphate flame retardants, aromatic amines and amides, pharmaceuticals, and bisphenol A have been identified based on their mass spectra. The developed method provides good performances in terms of extraction recovery (63.8-127%), intra-day and inter-day precisions (< 7.7 and < 13.9 respectively), linearity (R between 0.9669 and 0.9999), detection limit (1.01-69.30 μg L), quantification limit (1.87-138.6 μg L), and enrichment factor (69.6-138.5). Detailed information on the organic pollutants contained in municipal landfill leachate could be obtained with this method during a 40-min analysis of a 4-mL leachate sample, using only 75 μL of extraction solvent.