Microstructure, Wettability, Corrosion Resistance and Antibacterial Property of Cu-MTaO Multilayer Composite Coatings with Different Cu Incorporation Contents

Overview

Journal Biomolecules

Publisher MDPI

Specialties Biochemistry
Molecular Biology

Date 2020 Jan 8

PMID 31906220

Citations 5

Authors

Zeliang Ding

Yi Wang

Quan Zhou

Ziyu Ding

Jun Liu

Quanguo He

Haibo Zhang

Affiliations

Soon will be listed here.

Abstract

Bacterial infection and toxic metal ions releasing are the challenges in the clinical application of Ti6Al4V alloy implant materials. Copper is a kind of long-acting, broad-spectrum and safe antibacterial element, and TaO has good corrosion resistance, wear-resistance and biocompatibility, they are considered and chosen as a potential coating candidate for implant surface modification. In this paper, magnetron sputtering technology was used to prepare copper doped TaO multilayer composite coating Cu-TaO/TaO/TaO-TiO/TiO/Ti (Cu-MTaO for short) on Ti6Al4V alloy surface, for studying the effect of copper incorporation on the microstructure, wettability, anticorrosion and antibacterial activities of the composite coating. The results showed that Cu-MTaO coating obviously improves the hydrophobicity, corrosion resistance and antibacterial property of Ti6Al4V alloy. In the coating, both copper and TaO exhibit an amorphous structure and copper mainly presents as an oxidation state (CuO and CuO). With the increase of the doping amount of copper, the grain size, roughness, and hydrophobicity of the modified surface of Ti6Al4V alloy are increased. Electrochemical experiment results demonstrated that the corrosion resistance of Cu-MTaO coated Ti6Al4V alloy slightly decreased with the increase of copper concentration, but this coating still acts strong anticorrosion protection for Ti6Al4V alloy. Moreover, the Cu-MTaO coating can kill more than 97% of in 24 h, and the antibacterial rate increases with the increase of copper content. Therefore, Cu-MTaO composite coating is a good candidate for improving anticorrosion and antibacterial properties of Ti6Al4V alloy implant medical devices.

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References

He Q, Liu J, Liang J, Liu X, Li W, Liu Z . Towards Improvements for Penetrating the Blood-Brain Barrier-Recent Progress from a Material and Pharmaceutical Perspective. Cells. 2018; 7(4). PMC: 5946101. DOI: 10.3390/cells7040024. View

Zhang X, Li J, Wang X, Wang Y, Hang R, Huang X . Effects of copper nanoparticles in porous TiO coatings on bacterial resistance and cytocompatibility of osteoblasts and endothelial cells. Mater Sci Eng C Mater Biol Appl. 2017; 82:110-120. DOI: 10.1016/j.msec.2017.08.061. View

Haque S, Sagdeo P, Shinde D, Misal J, Jha S, Bhattacharyya D . Extended x-ray absorption fine structure measurements on asymmetric bipolar pulse direct current magnetron sputtered Ta(2)O(5) thin films. Appl Opt. 2015; 54(22):6744-51. DOI: 10.1364/AO.54.006744. View

Rosenbaum J, Versace D, Abbad-Andallousi S, Pires R, Azevedo C, Cenedese P . Antibacterial properties of nanostructured Cu-TiO surfaces for dental implants. Biomater Sci. 2017; 5(3):455-462. DOI: 10.1039/c6bm00868b. View

Xiao J, Zhu Y, Huddleston S, Li P, Xiao B, Farha O . Copper Metal-Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes. ACS Nano. 2018; 12(2):1023-1032. DOI: 10.1021/acsnano.7b01850. View

He Q, Tian Y, Wu Y, Liu J, Li G, Deng P . Facile and Ultrasensitive Determination of 4-Nitrophenol Based on Acetylene Black Paste and Graphene Hybrid Electrode. Nanomaterials (Basel). 2019; 9(3). PMC: 6473960. DOI: 10.3390/nano9030429. View

Ewald A, Kappel C, Vorndran E, Moseke C, Gelinsky M, Gbureck U . The effect of Cu(II)-loaded brushite scaffolds on growth and activity of osteoblastic cells. J Biomed Mater Res A. 2012; 100(9):2392-400. DOI: 10.1002/jbm.a.34184. View

Khanna R, Kokubo T, Matsushita T, Takadama H . Fabrication of dense α-alumina layer on Ti-6Al-4V alloy hybrid for bearing surfaces of artificial hip joint. Mater Sci Eng C Mater Biol Appl. 2016; 69:1229-39. DOI: 10.1016/j.msec.2016.08.025. View

Au A, Ha J, Hernandez M, Polotsky A, Hungerford D, Frondoza C . Nickel and vanadium metal ions induce apoptosis of T-lymphocyte Jurkat cells. J Biomed Mater Res A. 2006; 79(3):512-21. DOI: 10.1002/jbm.a.30811. View

10.

He Q, Wu Y, Tian Y, Li G, Liu J, Deng P . Facile Electrochemical Sensor for Nanomolar Rutin Detection Based on Magnetite Nanoparticles and Reduced Graphene Oxide Decorated Electrode. Nanomaterials (Basel). 2019; 9(1). PMC: 6359613. DOI: 10.3390/nano9010115. View

11.

Cao H, Liu X, Meng F, Chu P . Biological actions of silver nanoparticles embedded in titanium controlled by micro-galvanic effects. Biomaterials. 2010; 32(3):693-705. DOI: 10.1016/j.biomaterials.2010.09.066. View

12.

He Q, Liu J, Liu X, Li G, Chen D, Deng P . Fabrication of Amine-Modified Magnetite-Electrochemically Reduced Graphene Oxide Nanocomposite Modified Glassy Carbon Electrode for Sensitive Dopamine Determination. Nanomaterials (Basel). 2018; 8(4). PMC: 5923524. DOI: 10.3390/nano8040194. View

13.

Tao B, Lin C, Deng Y, Yuan Z, Shen X, Chen M . Copper-nanoparticle-embedded hydrogel for killing bacteria and promoting wound healing with photothermal therapy. J Mater Chem B. 2020; 7(15):2534-2548. DOI: 10.1039/c8tb03272f. View

14.

Berni M, Lopomo N, Marchiori G, Gambardella A, Boi M, Bianchi M . Tribological characterization of zirconia coatings deposited on Ti6Al4V components for orthopedic applications. Mater Sci Eng C Mater Biol Appl. 2016; 62:643-55. DOI: 10.1016/j.msec.2016.02.014. View

15.

Ghosh R, Swart O, Westgate S, Miller B, Yates M . Antibacterial Copper-Hydroxyapatite Composite Coatings via Electrochemical Synthesis. Langmuir. 2019; 35(17):5957-5966. DOI: 10.1021/acs.langmuir.9b00919. View

16.

Costerton J, Stewart P, Greenberg E . Bacterial biofilms: a common cause of persistent infections. Science. 1999; 284(5418):1318-22. DOI: 10.1126/science.284.5418.1318. View

17.

Hu X, Neoh K, Zhang J, Kang E . Bacterial and osteoblast behavior on titanium, cobalt-chromium alloy and stainless steel treated with alkali and heat: a comparative study for potential orthopedic applications. J Colloid Interface Sci. 2014; 417:410-9. DOI: 10.1016/j.jcis.2013.11.062. View

18.

Vincent M, Duval R, Hartemann P, Engels-Deutsch M . Contact killing and antimicrobial properties of copper. J Appl Microbiol. 2017; 124(5):1032-1046. DOI: 10.1111/jam.13681. View

19.

Taylor M, Urquhart A, Zelzer M, Davies M, Alexander M . Picoliter water contact angle measurement on polymers. Langmuir. 2007; 23(13):6875-8. DOI: 10.1021/la070100j. View

20.

Cai X, Zhang B, Liang Y, Zhang J, Yan Y, Chen X . Study on the antibacterial mechanism of copper ion- and neodymium ion-modified α-zirconium phosphate with better antibacterial activity and lower cytotoxicity. Colloids Surf B Biointerfaces. 2015; 132:281-9. DOI: 10.1016/j.colsurfb.2015.05.027. View